| 正确理解持续炎症-免疫抑制-分解代谢综合征免疫、炎症和代谢的关系 |
| |
| 作者姓名： | 刘军 |
| |
| 作者单位： | 1. 215001 苏州,南京医科大学附属苏州医院 苏州市立医院东区ICU |
| |
| 基金项目： | 江苏省苏州市科技发展计划项目(SS201874); 江苏省第五期"333工程"科研项目(BRA2016070); 苏州市卫生计生委科技项目(LCZX201607); 苏州市科技计划项目(SYS201569) |
| |
| 摘 要： | 持续炎症-免疫抑制-分解代谢综合征（PICS）是在全身性感染或非感染如创伤、烧伤、急性胰腺炎等进入慢性危重症阶段,以持续炎症反应、免疫抑制、蛋白质高分解代谢为特点的一组临床综合征。PICS患者免疫抑制、持续炎症及蛋白质高分解代谢之间存在复杂的交互对话,相互促进,互为因果。厘清PICS免疫、炎症和代谢之间的内在联系,具有重要临床意义。
|
| 关 键 词： | 持续炎症-免疫抑制-分解代谢综合征 慢性危重症 炎症 固有免疫 获得性免疫 分解代谢 |
| 收稿时间： | 2018-12-28 |
How to correctly understand the relationship between PICS immunity,inflammation and metabolism |
| |
| Authors: | Jun Liu |
| |
| Institution: | 1. Department of Critical Care Medicine, Suzhou Municipal Hospital, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou 215001, China |
| |
| Abstract: | Persistent inflammation- immunosuppression catabolism syndrome (PICS) is charactered by an immunocatabolic phenotype of persistent inflammation, immunosuppression, and catabolism in patients with chronic critical illness as a result of sepsis, trauma, burn, acute pancreatitis and so on. There is a complex interactive crosstalk between immune, inflammation and catabolism. It is of great clinical significance to clarify the internal association among immunity, inflammation and metabolism. |
| |
| Keywords: | Persistent inflammation-immunosuppression catabolism syndrome Chronic critical illness Inflammation Innate immune Acquired immune Catabolism |
|
| 点击此处可从《》浏览原始摘要信息 |
| 点击此处可从《》下载免费的PDF全文 |
