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结直肠癌患者急诊手术后口服营养补充剂的临床效果
引用本文:刘发强,路晓林,常迎彬.结直肠癌患者急诊手术后口服营养补充剂的临床效果[J].肿瘤防治研究,2019,46(7):610-613.
作者姓名:刘发强  路晓林  常迎彬
作者单位:1. 100142 北京,北京大学肿瘤医院暨北京市肿瘤防治研究所肝胆胰外科,软组织与腹膜后肿瘤中心,恶性肿瘤发病机制及转化研究教育部重点实验室;2. 100123 北京,民航总医院普通外科
摘    要:目的评价添加口服营养补充剂对结直肠癌患者急诊手术后康复的影响。方法回顾性对比分析2008年6月-2018年1月间进行急诊手术的38例结直肠癌患者,按营养支持方法分为TPN组和PN+ONS组,收集两组患者术前、术后第1天、术后第7天的血淋巴细胞数及白蛋白等指标,同时结合病历记载,获取患者并发症发生情况、总住院时间、术后住院时间等数据。结果两组患者一般资料(包括年龄、性别、手术时间、术中失血量(ml))等指标差异无统计学意义;PN+ONS组术后总并发症发生率和术后感染率低及总住院时间短,但两组间差异无统计学意义。结论结直肠癌患者急诊手术后适当添加口服营养补充剂,可能有利于减少患者的术后并发症、缩短住院时间。

关 键 词:结直肠癌  营养支持  口服营养补充剂  全胃肠外营养
收稿时间:2019-04-23

Clinical Effect of Oral Nutritional Supplements in Patients with Colorectal Cancer After Emergency Surgery
LIU Faqiang,LU Xiaolin,CHANG Yingbin.Clinical Effect of Oral Nutritional Supplements in Patients with Colorectal Cancer After Emergency Surgery[J].Cancer Research on Prevention and Treatment,2019,46(7):610-613.
Authors:LIU Faqiang  LU Xiaolin  CHANG Yingbin
Institution:1. Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Hepatobiliary and Pancreatic Surgery, Soft Tissue and Retroperitoneal Tumor Center, Peking University Cancer Hospital & Institute, Beijing 100142, China; 2. Department of General Surgery, Civil Aviation General Hospital, Beijing 100123, China 
Abstract:Objective To assess the clinical effect of oral nutritional supplements in patients with colorectal cancer after emergency surgery. Methods Based on a retrospective comparative analytic design, 38 CRC patients undergoing emergency surgery were divided into two groups according to nutrition support methods: TPN and PN+ONS groups. We collected the clinical data of two groups, including the number of blood lymphocyte and albumin before surgery and on the 1st and 7th postoperative day, postoperative complication, total length of stay and postoperative length of stay. Results The age, gender, operation time and the amount of operative blood loss volume did not show statistically significant difference between two groups(P>0.05). PN+ONS group had lower postoperative infection rate and complication rate and shorter total length of stay, but the difference was not statistically significant between two groups(P>0.05). Conclusion The application of ONS may be helpful to reduce postoperative complications and shorten the length of stay in CRC patients after emergency surgery.
Keywords:Colorectal cancer  Nutritional support  Oral nutritional supplements  Total parenteral nutrition  
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