鼻咽癌患者癌症复发恐惧水平及影响因素分析

目的 探讨鼻咽癌患者的癌症复发恐惧水平(fear of cancer recurrence,FCR)及影响因素,为制定针对性干预措施提供依据。 方法 选取2018年3—12月广州市2家三甲医院肿瘤科就诊的228例鼻咽癌患者作为研究对象,采用一般情况调查表、疾病进展恐惧简化量表(FoP-Q-SF)、领悟社会支持(PSSS)、简易应对方式问卷(SCSQ)进行调查,采用单因素分析、Pearson相关分析、多元逐步回归分析对鼻咽癌患者的FCR进行分析。 结果 鼻咽癌患者FCR得分为(37.14±9.28)分;单因素分析结果显示,鼻咽癌患者的FCR得分在年龄、受教育程度、月收入、肿瘤临床分期4个变量上存在差异(均P＜0.05);Pearson相关分析显示,鼻咽癌患者的FCR与家庭内支持、家庭外支持、领悟社会支持总分、积极应对呈负相关(均P＜0.05),与消极应对呈正相关(P＜0.05);多元逐步回归分析显示,积极应对、肿瘤临床分期、社会支持、受教育程度依次进入回归方程(F=29.842,P<0.001;R2=0.368,调整R2=0.356)。 结论 鼻咽癌患者的FCR水平较高,积极应对、肿瘤临床分期、社会支持、受教育程度是鼻咽癌患者的FCR的主要影响因素。医护人员应关注鼻咽癌患者的FCR水平,制定针对性的干预措施,帮助患者建立和维持良好的社会支持系统,鼓励患者积极应对,从而降低和控制患者的FCR水平。 

Analysis of the fear of cancer recurrence and contributory factors in patients with nasopharyngeal carcinoma

Objective To investigate the fear of cancer recurrence (FCR) and its contributory factor in patients with nasopharyngeal carcinoma, and to provide evidence for targeted intervention. Methods A total of 228 patients with nasopharyngeal carcinoma who were admitted to the oncology department of two top three hospitals in our city between March to December 2018 were recruited and the FCR was surveyed by using the General Survey, Fear of Progression Questionnaire-Short Form (FoP-Q-SF), Perceived Social Support Scale (PSSS) and Simplified Coping Style Questionnaire (SCSQ). The single factor analysis, Pearson correlation analysis and multiple stepwise regression analysis were performed to analyze the contributory factor for the FCR score of patients with nasopharyngeal carcinoma. Results The FCR score of patients with nasopharyngeal carcinoma was (37.14±9.28) points; Single factor analysis showed that the FCR scores of patients with nasopharyngeal carcinoma were different in age, education level, monthly income, and tumor clinical stage (all P<0.05); Pearson correlation analysis showed that the FCR of patients with nasopharyngeal carcinoma was negatively correlated with in-home support, out-of-home support, perceived social support total scores, and positive coping (P<0.05), and positively correlated with negative coping (all P<0.05); Multiple stepwise regression analysis showed that the positive coping, tumor clinical stage, social support, and education level entered the regression equation in turn (F=29.842, P<0.001; R2=0.368, adjusted R2=0.356). Conclusions The patients with nasopharyngeal carcinoma have higher FCR level, positive coping, clinical stage of tumors, social support, and education level are the main contributory factor of FCR in patients with nasopharyngeal carcinoma. Health care workers should pay more attentions to the FCR level of patients with nasopharyngeal carcinoma, and develop targeted interventions to help patients establish and maintain a good social support system, encourage patients to respond positively, and thus reduce and control the patient's FCR level.