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Fasudil hydrochloride hydrate, a Rho-kinase (ROCK) inhibitor, suppresses collagen production and enhances collagenase activity in hepatic stellate cells. |
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| Authors: | Marie Fukushima Makoto Nakamuta Motoyuki Kohjima Kazuhiro Kotoh Munechika Enjoji Naoya Kobayashi Hajime Nawata |
| Affiliation: | Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. |
| Abstract: | |
| Keywords: | collagen collagenase activity fasudil hepatic stellate cell (HSC) MMP‐1 ROCK inhibitor TIMP‐1 |