| 复方龙星片质量标准研究 |
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| 引用本文： | 徐光临,易月,刘力,徐德生.复方龙星片质量标准研究[J].中国药业,2014(8):31-33. |
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| 作者姓名： | 徐光临 易月 刘力 徐德生 |
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| 作者单位： | 上海中医药大学附属曙光医院药剂科,上海200021 |
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| 基金项目： | 上海市科技专项计划项目,项目编号：12401901401;上海市卫生局基金,项目编号：2006Y001A. |
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| 摘 要： | 目的建立复方龙星片的质量标准。方法采用薄层色谱法对方中地龙、黄芩进行定性鉴别；采用高效液相色谱法分别测定复方龙星片中次黄嘌呤及黄芩苷的含量。结果确立了制剂中地龙、黄芩的定性鉴别方法。次黄嘌呤进样量线性范围为0．0206～2．06μg（r=0．99995），平均加样回收率为95．75％，RSD为2．66％（n=9）；黄芩苷进样量线性范围为0．0654～1．9621,zg（r=1．0000），平均加样回收率为98．07％，RSD为1．49％（n=9）。结论该方法简便、准确，可有效控制复方龙星片的质量。
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| 关 键 词： | 复方龙星片 薄层色谱法 高效液相色谱法 质量标准 |
Study on Quality Standard of Compound Longxing Tablets |
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| Xu Guanglin,Yi Yue,Liu Li,Xu Desheng.Study on Quality Standard of Compound Longxing Tablets[J].China Pharmaceuticals,2014(8):31-33. |
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| Authors: | Xu Guanglin Yi Yue Liu Li Xu Desheng |
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| Institution: | ( Department of Pharmacy, Affiliated Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China 200021 ) |
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| Abstract: | Objective To establish the quality standard of Compound Longxing Tablets. Methods The thin- layer chromatography（TLC） was adopted for conducting the qualitative identification; the content of hypoxanthine and baicalin was determined by HPLC. Results The identifying method of pheretima and radix scutellariae was established. The linear range of hypoxanthine was 0. 020 6- 2.06 μg （r=0. 999 95） and the average recovery rate was 95.75 %, RSD=2.66% （n=9）. The linear range of baicalin was 0.065 4- 1. 962 μg（ r = 1. 000 0） and the average recovery rate was 98.07%, RSD = 1.49% （n =9）. Conclusion This method is simple and accurate, and can effectively control the quality of Ccompound Longxing Tablets. |
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| Keywords: | Compound Longxing Tablets TLC HPLC quality standard |
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