| 消渴脉康颗粒质量标准研 究简 |
| |
| 引用本文： | 何洋,何绍斌,金文,林以慈,罗钧锦,石钺. 消渴脉康颗粒质量标准研 究简[J]. 中国药业, 2014, 0(5): 29-31 |
| |
| 作者姓名： | 何洋 何绍斌 金文 林以慈 罗钧锦 石钺 |
| |
| 作者单位： | [1]中国医学科学院药用植物研究所,北京100193 [2]广州市悠好福医药科技有限公司,广东广州510610 |
| |
| 基金项目： | 科技部“重大新药创制”科技重大专项项目,项目编号：2012ZX09301002-001. |
| |
| 摘 要： | 目的 建立消渴脉康颗粒的质量控制方法.方法 采用薄层色谱（TLC）法对组方中牛膝、丹参、枸杞子、桑寄生、延胡索和黄芪进行定性鉴别,采用高效液相色谱（HPLC）法对芍药苷进行定量测定.结果 薄层色谱清晰,分离良好,阴性无干扰.芍药苷的平均回收率为96.95％,RSD为1.81％.结论 该方法简便易行、灵敏准确、专属性强,可用于消渴脉康颗粒的质量控制.
|
| 关 键 词： | 消渴脉康颗粒 薄层色谱 高效液相色谱法 质量控制 |
Quality Standard of Xiaoke Maikang Granules |
| |
| He Yang,He Shaobin,Jin Wen,Lin Yici,Luo Junjin,Shi Yue. Quality Standard of Xiaoke Maikang Granules[J]. China Pharmaceuticals, 2014, 0(5): 29-31 |
| |
| Authors: | He Yang He Shaobin Jin Wen Lin Yici Luo Junjin Shi Yue |
| |
| Affiliation: | 1. Research Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing, China 100193; 2. Gnangzhou Youhaofu Pharmaceutical Technology Co. , Ltd. , Gnangzhou, Guangdong, China 510610) |
| |
| Abstract: | Objective To establish a method for the dissolution determination of Clarithromycin Granules.Methods With acetate buffer solution（pH =5.0） as the dissolution medium and the dissolution time of 30 rmin,the determination was performed by high performance liquid chromatography（HPLC）.Results The linear range of clarithromycin was 20.60-92.68 μg/mL,the linear equation is A =1.998 7 C ＋ 0.152 1,r =0.999 3（n =8）.Conclusion The tnethod is simple,fast,accurate and can be applied to determine the dissolution of Clarithromycin Granules. |
| |
| Keywords: | Clarithromycin Granules dissolution high performance liquid chromatography |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
