输卵管妊娠腹腔镜保守手术切除黄体联合甲氨蝶呤防治持续性异位妊娠72例

目的观察输卵管妊娠腹腔镜保守手术切除黄体联合应用甲氨蝶呤（MTX）防治持续性异位妊娠（PEP）的临床效果。方法回顾性分析139例输卵管妊娠腹腔镜保守手术患者的资料，其中输卵管妊娠腹腔镜保守手术切除黄体联合应用MTX72例为研究组，输卵管妊娠腹腔镜保守手术应用MTX67例为对照组，比较两组输卵管妊娠的治疗效果。结果术后β-HCG降至正常所需时间研究组为（10．24±4．5）d，对照组为（14．1±5．6）d，差异有统计学意义（P〈0．05）；研究组无PEP发生，对照组发生率为8．96％（P〈0．05）。结论输卵管妊娠腹腔镜保守手术切除黄体联合应用MTX防治PEP效果确切，优于输卵管妊娠保守手术应用MTX。

Corpus Luteum Excision by Laparoscopic Tubal Pregnancy Conservative Operation Combined with MTX for Preventing and Treating PEP in 72 Cases

Objective To evaluate the clinical effect of corpus luteum resection by laparoscopic tubal pregnancy conservative operation combined with methotrexate（MTX） for preventing and treating persistent ectopic pregnancy （PEP）. Methods The data in 139 cases of laparoscopic tubal pregnancy conservative operation were performed the retrospective analysis, in which, 72 cases of corpus lnteum resec- tion by laparoscopic tubal pregnancy conservative operation combined with MTX were taken as the study group and 67 cases of laparo- scopic tubal pregnancy conservative operation combined with MTX as the control group. The curative effects of tubal pregnancy were compared between the two groups. Results The time of beta- HCG dropped to normal after operation was （10.2 ± 4.5）d in the study group and （14. 1 ±5.6）d in the control group, the difference between the two groups has statistically significant（P〈0.05）. No case of PEP occurred in the study group, while the occurrence rate of PEP in the control group was 8.96%, the difference between the two groups has statistically significant（ P 〈 0.05）. Conclusion Corpus luteum excision by laparoscopic tubal pregnancy conservative operation combined with MTX has definite effect for preventing and treating PEP and is better than the tubal pregnancy conservative operation combined with MTX.