| NVB联合铂类方案与CAP方案治疗晚期NSCLC近期疗效比较 |
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| 引用本文： | 李强,孟祥菊,贾雪峰,赵海波,张红梅,国桂松. NVB联合铂类方案与CAP方案治疗晚期NSCLC近期疗效比较[J]. 肿瘤基础与临床, 2003, 16(2): 95-97 |
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| 作者姓名： | 李强 孟祥菊 贾雪峰 赵海波 张红梅 国桂松 |
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| 作者单位： | 济宁市第一人民医院肿瘤科,山东,济宁,272111 |
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| 摘 要： | 目的 比较去甲长春花碱 (NVB)联合铂类方案和CAP(环磷酰胺 ,阿霉素和顺铂 )方案对晚期非小细胞肺癌 (non -small -celllunfcancer ,NSCLC)的疗效与毒性。方法 统计分析用NVB联合铂类方案及CAP方案治疗的 49例晚期NSCLC临床资料。结果 NVB联合铂类方案组有效率为 48 15 % ( 13/2 7) ,其中CR 1例 ;CAP方案组有效率为 36 36% ( 8/2 2 ) ,毒性反应主要为骨髓受抑和恶心呕吐。结论 NVB联合铂类方案是治疗晚期NSCLC的一种有效、安全的化疗方案
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| 关 键 词： | 去甲长春花碱 铂类 晚期非小细胞肺癌 |
| 文章编号： | 1003-1464(2003)02-0095-03 |
| 修稿时间： | 2002-05-08 |
Comparative Study of Navelbine(NVB) Plus Platinum Protocol and Cyclophosphamide,Adriamycin and Cisplatin Protocol (CAP) for Advanced Non-small-cell Lung Cancer |
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| LI Qiang,MENG Xiang-ju,JIA Xue-feng,et al. Comparative Study of Navelbine(NVB) Plus Platinum Protocol and Cyclophosphamide,Adriamycin and Cisplatin Protocol (CAP) for Advanced Non-small-cell Lung Cancer[J]. journal of basic and clinical oncology, 2003, 16(2): 95-97 |
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| Authors: | LI Qiang MENG Xiang-ju JIA Xue-feng et al |
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| Abstract: | Objective To compare the efficacy and toxicity of NVB plus platinum protocol with CAP protocol for advanced non-small-cell lung cancer.Methods The clinical data of 79 cases with advanced NSCLC treated with NVB plus platinum (27 cases) and CAP (22 cases) were analyzed.Results The response rate was 48.15% in patients treated with NVB plus platinum,and 36.36% in those with CAP,respectively.The major toxic reactions in the two chemotherapeutic protocols for the treatment of advanced NSCLC patients.Conclusion NVB plus platinum protocol is a effective and safe chemotherapeutic protocol for the treatment of advanced NSCLC. |
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| Keywords: | navelbine platinum advanced non-small-cell lung cancer |
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