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Use of Remdesivir in Myasthenia gravis and COVID-19
Authors:Bradley J. Peters  Alejandro A. Rabinstein  Hilary M. DuBrock
Affiliation:1. Department of Pharmacy, Mayo Clinic, Rochester, Minnesota, USA;2. Division of Neurology, Mayo Clinic, Rochester, Minnesota, USA;3. Division of Pulmonary & Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, USA

Division of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA

Abstract:Myasthenia gravis and the associated pharmacologic management options could place patients at higher risk of contracting severe acute respiratory syndrome coronavirus 2 and exhibiting more severe manifestations of the novel coronavirus disease 2019 (COVID-19). Multiple agents have been studied for the management of the COVID-19, including remdesivir. To date, no published reports have evaluated the utilization of the antiviral remdesivir in patients with myasthenia gravis. We describe the first reported clinical course of three patients with myasthenia gravis who safely received remdesivir in combination with dexamethasone for the management of COVID-19.
Keywords:coronavirus  COVID  COVID-19  Myasthenia gravis  Remdesivir  SARS
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