Cleft lip and palate: series of unusual clinical cases |
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Authors: | Lívia Máris Ribeiro Paranaíba Roseli Teixeira de Miranda Daniella Reis Barbosa Martelli Paulo Rogério Ferreti Bonan Hudson de Almeida Julian Miranda Orsi Júnior Hercílio Martelli Júnior |
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Affiliation: | 1. MSc in Stomatology -State University of Campinas - Unicamp; PhD student in Stomatology - Unicamp;2. PhD in Oral Diagnosis - University of São Paulo - USP, Professor of Stomatology - University of Alfenas;3. MSc in Health Sciences -State University of Montes Claros - Unimontes, Professor of Semiology - Unimontes;4. PhD in Stomatology - State University of Campinas - Unicamp, Adjunct Professor - State University of Montes Claros - Unimontes;5. Resident Physician in Plastic Surgery - Professor at the Medical Sciences School - University of Alfenas;6. MSc in Health - University of Alfenas; Professor at the Dentistry School - University of Alfenas;7. PhD; Full Professor. Centro de Ciências Biológicas e da Saúde (CCBS) - Universidade Estadual de Montes Claros, Unimontes, Minas Gerais, Brasil. Campus Universitário Darcy Ribeiro, s/n Vila Mauricéia Montes Claros MG 39400-000. Fundação de Amparo à Pesquisa do Estado de Minas Gerais - Fapemig |
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Abstract: | Cleft lip and/or palate (CL/P) represent the most common congenital anomalies of the face, corresponding to approximately 65% of all malformations of the craniofacial region.Aimto describe unusual clinical cases of non-syndromic CL/P (CL/PNS), diagnosed in a reference service in Minas Gerais, Brazil, and correlate these alterations with possible risk factors.Materials and Methodswe carried out a retrospective study, between the years of 1992 and the 1st half of 2009, from medical records.ResultsAmong the 778 cases of CL/PNS diagnosed in the period of 17 years, 5 (0.64%) were unusual CL/PNS, and all patients were male. It was found that among the 5 patients, 2 had incomplete right cleft lip with incomplete cleft palate, 2 were affected by left incomplete cleft lip and incomplete cleft palate, and 1 had a cleft lip and palate associated with complete right cleft palate. Risk factors such as consanguinity, maternal smoking and alcohol consumption, medication usage during pregnancy, history of abortion and/or stillbirths and maternal diseases were not associated with unusual CL/PNS.ConclusionsThis study described 5 unusual cases of CL/PNS in a Brazilian population; no associations with the risk factors analyzed were seen. It also confirmed the unusualness of the prevalence of such alterations. |
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Keywords: | congenital abnormalities cleft lip cleft palate. |
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