Rhabdomyosarcoma of the head and neck: 24 cases and literature review |
| |
| Authors: | Giovana Moretti Ricardo Guimarães Karisa Martins de Oliveira Fernanda Sanjar Richard Louis Voegels |
| |
| Affiliation: | 1. Otorhinolaryngologist, fellowship in endonasal endoscopic surgery, otorhinolaryngological unit, Clinical Hospital, Medical School, São Paulo University (HCFMUSP);2. Otorhinolaryngologist, fellowship in endonasal endoscopic surgery, otorhinolaryngological unit, HCFMUSP;3. Pediatric oncologist at the Child Cancer Therapy Insttute, Itaci/Child Insttute, ICR-HCFMUSP;4. Otorhinolaryngologist at the otorhinolaryngological unit, HCFMUSP;5. Assistant professor in otorhinolaryngologist at the otorhinolaryngological unit, HCFMUSP |
| |
| Abstract: | Rhabdomyosarcoma (RMS) is a malignant tumor of soft tissues, more common in childhood, mainly located in the head and neck. It presents varied clinical and biological behavior and requires individualized management.AimTo describe information on patients with head and neck RMS diagnosed and treated in a hospital, and to compare them to results in the literature. Study design: Descriptive and retrospective.Materials and MethodsA retrospective analysis of data from 24 patients with head and neck rhabdomyosarcoma diagnosed and treated in a hospital from 1994 to 2008.ResultsThe mean age was 7.79 years. According to gender, 54.17 % were males and 45.83 % were female. All patients underwent chemotherapy (CT), 62.5% of them also underwent radiotherapy (RT) and 16.67% were submitted to surgery. Of the 24 patients, 8 (33.3%) died, 6 (25%) were found free of neoplasia and 2 (8.3%) experienced tumor recurrence.ConclusionThe RMS of the head and neck often presents with nonspecific symptoms. Individualized multimodal therapy should be performed for these patients, including surgery, chemotherapy and radiotherapy. |
| |
| Keywords: | head and neck neoplasms soft tissue neoplasms rhabdomyosarcoma |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
