| 参麦汤对糖耐量异常大鼠骨骼肌GLUT4mRNA基因表达的影响 |
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| 引用本文： | 柴可夫,孙炜,马纲,慎知,谷英敏. 参麦汤对糖耐量异常大鼠骨骼肌GLUT4mRNA基因表达的影响[J]. 中华中医药学刊, 2011, 0(2): 231-234 |
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| 作者姓名： | 柴可夫 孙炜 马纲 慎知 谷英敏 |
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| 作者单位： | 浙江中医药大学; |
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| 基金项目： | 浙江省中医“治未病”专项研究计划(2007WA004) |
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| 摘 要： | 目的:探讨参麦汤改善糖耐量异常大鼠骨骼肌GLUT4mRNA基因表达的作用。方法:造模大鼠随机分为正常组、模型组、参麦汤组、参麦汤加运动组、运动组。用RT-PCR方法检测参麦汤对糖耐量异常大鼠骨骼肌GLUT4mRNA表达的影响。结果:参麦汤组大鼠骨骼肌GLUT4mRNA表达上升最显著(P<0.001),运动组(P<0.01)、参麦加运动组(P<0.05)依次次之。结论:参麦汤可上调大鼠骨骼肌GLUT4mRNA的表达,可能是其改善胰岛素抵抗的机理之一。
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| 关 键 词： | 糖耐量异常 参麦汤 葡萄糖转运蛋白4mRNA 基因表达 |
The Impact of Shenmai Decoction on Impaired Glucose Tolerance in Rat with Insulin Resistance Related Factors |
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| CHAI Ke-fu,SUN Wei,MA Gang,SHEN Zhi,GU Ying-min. The Impact of Shenmai Decoction on Impaired Glucose Tolerance in Rat with Insulin Resistance Related Factors[J]. Chinese Archives of Traditional Chinese Medicine, 2011, 0(2): 231-234 |
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| Authors: | CHAI Ke-fu SUN Wei MA Gang SHEN Zhi GU Ying-min |
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| Affiliation: | CHAI Ke-fu,SUN Wei,MA Gang,SHEN Zhi,GU Ying-min(Zhejiang Chinese Medical University,Hangzhou 310053,Zhejiang,China) |
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| Abstract: | Objective: To evaluate the improvement of impaired glucose tolerance Shenmai Tom GLUT4mRNA gene expression in skeletal muscle function.Methods: The rats were randomly divided into normal group,model group,Shenmai treated,Shenmai Tonga exercise group,exercise group.Using RT-PCR to detect impaired glucose tolerance Shenmai decoction on expression of skeletal muscle GLUT4mRNA.Results: Shenmai soup increased the expression of rat skeletal muscle GLUT4mRNA most significant(P<0.001),exercise group(P<0.01),partici... |
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| Keywords: | impaired glucose tolerance Shenmai soup GLUT4mRNA gene expression |
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