心电图和心肌标志物与急性冠脉综合征的关系分析

目的对急性冠脉综合征(ACS)患者的心电图(ECG)和肌钙蛋白I(cTnI)的关系进行分析,以探讨其对ACS患者血管病变程度的诊断价值。方法对37例ACS确诊患者的ECG和cTnI进行检测,分析ECG和cTnI阳性与血管闭塞和血管狭窄的关系,及两指标间的一致性。统计分析采用χ2检验和logistic回归分析。结果ECG与cTnI阳性的患者,其血管闭塞发生率(P=0.016;P=0.003)和血管狭窄发生率(P=0.121;P=0.013)均较ECG与cTnI阴性的患者高。但在血管闭塞和血管狭窄与ECG和cTnI的logistic分析中,仅cTnI差异有统计学意义(P=0.013;P=0.021)。ECG与cTnI具有较好的一致性(Kappa=0.617,P<0.001)。结论ECG与cTnI定性检测均能较好地反映ACS患者的血管病变程度,具有临床指导意义。

Relationship of ECG and Troponin I with Acute Coronary Syndrome

Objective To analyze the electrocardiogram (ECG) and troponin (cTnI) in patients with acute coronary syndrome (ACS), so as to assess their value in diagnosing the extent of vascular lesions. Methods The results of ECG, cTnI and coronary angiography (CAG) were analyzed in 37 patients with ACS. Chi-square test and a logistic regression model were used for statistical analysis. Results In patients with positive ECG or cTnI, the results of Chi- square test showed that the incidences of coronary occlusion (P=0.016, 0.003, respectively) and coronary stenosis (P=0.121, 0.013, respectively) were significantly higher than for those with negative ECG or cTnI. The results of logistic regression analysis indicated that only cTnI was significantly correlated with coronary occlusion (P=0.013) and moderate to severe coronary stenosis (P=0.021). ECG has significant consistency with cTnI (Kappa=0.617, P<0.001). Conclusion Both ECG and the qualitative cTnI test can reflect the extent of vascular lesions in patients with ACS.