阴囊Paget病15例临床资料分析

目的 :探讨阴囊Paget病的临床特点和诊治方法。　方法 :对 15例阴囊Paget病患者的临床、病理资料以及治疗和随访进行回顾性研究 ,全部患者先行患处活检 ,后行手术治疗。　结果 :15例患者病理检查均可见Paget病的典型特征 ;13例获随访 ,随访时间 0 .5～ 13年 ;2例术后 2年死于广泛转移 ,3例术后死于心脑血管病 ,1例术后 3年局部复发 ,再行手术切除 ;其余 7例无复发。　结论 :阴囊Paget病应尽早行皮肤活检确诊 ,局部广泛切除是本病首选治疗方法 ,手术效果好 ,预后满意 ,对局部复发可行二次手术。

Clinical Analysis of 15 Cases of Paget''''s Disease of the Scrotum

OBJECTIVE: To study the clinicopathologic features and treatment of Paget's disease of the scrotum. METHODS: Fifteen cases of Paget's disease of the scrotum, pathologically diagnosed and successfully treated by surgery from 1987 to 2003, were studied retrospectively. RESULTS: Typical pathological features were observed in all the patients. Thirteen cases were followed up for 0. 5 approximately 13 years, of whom 1 case relapsed within 3 years, 2 died of metastasis after 2 years, and 3 died of cardiovascular diseases, with no recurrence in the others. CONCLUSION: Early biopsy and extensive excision of the scrotal lesion is the first choice of treatment for Paget's disease, with good operative effect and satisfactory prognosis. A 2nd operation could be considered for patients of local relapse.