中药组方对腹腔镜保守手术治疗输卵管妊娠结局的影响

目的：观察腹腔镜保守手术后联合应用中药组方对输卵管妊娠结局的影响。方法：将198例腹腔镜保守手术治疗的输卵管妊娠患者随机分为三组（A、B、C）,A组（手术＋术后中药组方治疗）55例,B组（手术＋术中MTX15mg患侧输卵管系膜内注射治疗）57例,C组（单纯腹腔镜保守手术）86例。结果：A、B两组均无PEP发生,C组PEP发生率为10.47%。A、B两组发生率明显低于C组（P〈0.05）。A、B两组术后96h血β-hCG下降率明显高于C组（P〈0.05）。B组治疗后不良反应发生率明显高于A、C两组（P〈0.05）。结论：腹腔镜保守手术后联合应用中药组方治疗输卵管妊娠,可明显加快术后血β-hCG下降速度;可预防PEP的发生,其有效率与MTX组相同,且不良反应发生率明显降低,值得临床推广应用。

Impact of Chinese Traditional Medicine Formulae on Postoperative Tubal Pregnancy Treated by Conservative Laparoscopy

Objective： Observation on impact of Chinese traditional medicine formulae on postoperative tubal pregnancy treated by conservative laparoscopy.Method：198 cases of tubal pregnancy treated by conservative laparoscopy were randomly divided into 3 groups（A,B,C）,group A（patients accepted operation and Chinese traditional medicine formulae after operation） with 55 cases;group B（patients accepted operation and 15mg methotrexate was injected in mesenterium to the ipsilateral tubal during operation） with 57 cases;group C（only operation,regarded as control group） with 86 cases.Result：There was no occurrence of persistent ectopic pregnancy in group A and B,the incidence of persistent ectopic pregnancy in group C was 10.47%.The incidence of persistent ectopic pregnancy in group A and B was obviously lower than that of group C（P0.05）.The rate of decline of β-HCG in blood in 96 hours after operation in group A and B was obviously higher than that of group C（P0.05）.The incidence of adverse effect in group B was obviously higher than that of group A and C（P0.05）.Conclusion：Chinese traditional medicine formulae is used on postoperative tubal pregnancy treated by conservative laparoscopy,which can obviously accelerate the speed of decline of β-HCG in blood,which can prevent the occurrence of persistent ectopic pregnancy,whose efficacy is the same as the methotrexate group,but lower adverse effect,which is worth to be applied clinically.