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~(99)TC~m-MDP SPECT/CT图像融合对非典型骨转移肿瘤的诊断价值
引用本文:余颂科,陈晓良,蒋世曦.~(99)TC~m-MDP SPECT/CT图像融合对非典型骨转移肿瘤的诊断价值[J].检验医学与临床,2016(7).
作者姓名:余颂科  陈晓良  蒋世曦
作者单位:1. 重庆市肿瘤医院研究所/癌症中心 核医学科 400030;2. 重庆市肿瘤医院研究所/癌症中心 影像科 400030
基金项目:重庆市卫生和计划生育委员会医学科研面上资助项目(2010-2-307)。
摘    要:目的探讨~(99)TC~m-MDP SPECT/CT图像融合对非典型骨转移肿瘤的诊断价值。方法对静脉注射~(99)TC~m-MDP的106例全身骨扫描为单发病灶的非典型骨转移的恶性肿瘤患者,行SPECT/CT图像融合显像,对所成的SPECT、SPECT+CT、SPECT/CT影像进行分析总结,将诊断结果与最终病理及其他检查和随访结果进行比较。结果所有患者中共发现病灶124个,较全身骨显像多发现18个病灶,其中SPECT、CT、SPECT/CT的阳性率分别为91.1%、84.7%、100.0%,诊断符合率分别为38.7%、82.3%、92.7%。结论 SPECT/CT融合显像可以明显提高非典型骨转移肿瘤诊断准确性。为发现早期骨转移肿瘤灶提供了很好检查方法。

关 键 词:放射性核素  骨显像  SPECT/CT  骨转移肿瘤

Value of 99 TCm-MDP SPECT/CT imaging fusion in diagnosis of atypical bone metastasis tumor
Abstract:Objective To evaluate the value of 99 TCm methylene diphosphonic acid(MDP)‐SPECT/CT imaging fusion in the diagnosis of atypical bone metastasis tumor .Methods 106 cases of malignant tumor with one lesion of atypical bone metastasis by whole body bone scanning after intravenous injection of 99 TCm‐MDP were performed the SPECT/CT fusion imaging ,the obtained SPECT ,SPECT+CT and SPECT/CT image was analyzed and summarized . The diagnostic results were compared with the final pathological and other examination results and follow up results . Results 124 lesions were found in all cases .Compared with the whole body bone scanning ,more than18 bone lesions were discovered ,in which the positive rates of SPECT ,CT and SPECT/CT were 91 .1% ,84 .7% and 100 .0% respec‐tively .Their diagnostic coincidence rates were 38 .7% ,82 .3% and 92 .7% respectively .Conclusion The fusion ima‐ging of SPECT/CT may improve the accuracy for diagnosing atypical bone metastasis tumor and provides a very good method for early find bone metastasis tumor lesion .
Keywords:radionuclide  bone image  SPECT/CT  bone metastasis
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