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Propofol infusion syndrome: A lethal condition in critically injured patients eliminated by a simple screening protocol
Authors:Thomas J. Schroeppel  Timothy C. Fabian  L. Paige Clement  Peter E. Fischer  Louis J. Magnotti  John P. Sharpe  Marilyn Lee  Martin A. Croce
Affiliation:1. Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, United States;2. Department of Pharmacy, Regional Medical Center at Memphis, Memphis, TN, United States;3. Department of Surgery, Carolinas Medical Center, Charlotte, NC, United States
Abstract:Propofol infusion syndrome (PIS) is defined by arrhythmia, rhabdomyolysis, lactic acidosis, and unrecognized leads to death. We sought to determine the incidence of PIS in trauma patients and evaluate the efficacy of a prospective screening protocol in this patient population.
Keywords:Propofol   Sedation   Trauma
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