针刺对糖尿病周围神经病变的影响

目的:观察针刺治疗糖尿病周围神经病变(DPN)的疗效,并探讨其作用机理.方法:针刺肩髃、曲池、外关、合谷、环跳、足三里、三阴交、阳陵泉等治疗DPN患者68例,检测治疗前后血糖、血脂、血流变等及神经传导速度的变化.结果:显效43例,有效20例,无效5例,总有效率92.6%;神经传导速度提高,胰岛素、C肽、吗啡肽水平提高,与治疗前相比,差异有非常显著性意义(P＜0.01);血液黏稠度降低,与治疗前相比,差异有非常显著性意义(P＜0.01).结论:针刺治疗DPN疗效确切,其神经传导速度的提高可能与其血浆吗啡肽水平的提高有关.

Effects of acupuncture on diabetic peripheral neuropathies

Objective To observe therapeutic effect of acupuncture on diabetic peripheral neuropathy (DPN) and explore the mechanism. Methods Sixty-eight cases of DPN were treated with acupuncture at Jianyu (LI 15), Quchi (LI 11), Waiguan (TE 5) ect. and their blood sugar, blood lipids and hemorrheologic indexes and nerve conductive velocity before and after treatment were determined. Results After treatment, 43 cases were markedly effective, 20 cases were effective and 5 cases were ineffective, with a totam effective rate of 92.6%; the nerve conductive velocity, plasma insulin, C-peptide, opioid peptides increased significantly (P<0.01) and blood viscosity significantly decreased (P<0.01). Conclusion Acupuncture has a definite therapeutic effect on DPN and the increase of nerve conductive velocity is possibly related with the increase of plasma opioid peptides.