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Recurrence Rates and Prognostic Factors in ypN0 Rectal Cancer After Neoadjuvant Chemoradiation and Total Mesorectal Excision |
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| Authors: | Anand Govindarajan Diane Reidy Martin R. Weiser Philip B. Paty Larissa K. Temple Jose G. Guillem Leonard B. Saltz W. Douglas Wong Garrett M. Nash |
| Affiliation: | (1) Department of Colorectal Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA;(2) Department of Medical Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA; |
| Abstract: | BackgroundNeoadjuvant chemoradiation followed by surgery and adjuvant chemotherapy is typically recommended for patients with locally advanced rectal cancer. Patients with pathologically node-negative tumors have an improved prognosis, but recurrence patterns and independent prognostic factors in these patients have been incompletely characterized. |
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