195例念珠菌药敏分析

目的：探讨念珠菌与医院感染之间的关系，为临床提供诊断和治疗依据。方法：TTC沙保罗培养基、API20CAUX酵母鉴定系统以及ATBFUNGUS药敏试验条，按说明操作。结果：195株念珠菌中白色念珠菌132株（67．7％），热带念珠菌为36株（18．5％），平滑念珠菌11株（5．6％），克柔念珠菌16株（8．2％）。195株念珠菌药敏测试结果为，5－氟胞嘧啶的耐药率为9．7％，二性霉素耐药率为6．2％，制霉菌素耐药率为4．1％，咪康唑耐药率为18．5％，益康唑耐药率为21．0％，酮康唑耐药率最高为22．6％。结论：广谱抗生素的使用，使体内菌群失调，造成深部的二重感染。临床应慎用广谱抗生素，应选择疗效肯定、窄谱抗菌药物。

Drug Sensitiztion Analysis of 195 Cases Candida

Objective:To probe the relationship between candida and hospital infection,and prodvide the diagnosis and treatment proof for the clinic.Methods:Culturing with TTC sabouraud medium,according to the direction,based on API20C AUX yeast idemtification system ATB FUNGUS drug sensitization was tested.Results:C.albicans are 132 strains (67.7%),C.tropicalis 36 strains (18.5%),C.glubrata 11 strains (5.6%),C.krusei 16 strains (8.2%),among 195 candida strains.In the drug sensitization test,5-Flucytosin (5-FC)drugresistant rate is 9.7%,Amphotricin B(AMB)6.2%,Nystatin(NYS)4.1%,Miconazol(MIC)18.5%,Econazol(ECO)21.0%,Ketoconazol (KET)22.6%(highest point).Conclusion: Using of broadantibioctic causes flora imbalance in the body,even causes double infection of deep yeasts.Broad-antibiotic should be used carefully in the clinic,Narrowanbacteria drugs that have better curative effect should be choosed.