| 牛白藤抗炎活性化学成分的研究 |
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| 引用本文： | 陶曙红,陈艳芬,李钟,杨超燕,严优芍,吴燕文,徐佩婷.牛白藤抗炎活性化学成分的研究[J].广东药学院学报,2011,27(4):364-366. |
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| 作者姓名： | 陶曙红 陈艳芬 李钟 杨超燕 严优芍 吴燕文 徐佩婷 |
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| 作者单位： | 广东药学院中药学院,广东广州,510006 |
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| 基金项目： | 广东省中医药管理局项目 |
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| 摘 要： | 目的 研究牛白藤抗炎活性的化学成分.方法 利用硅胶柱色谱法对牛白藤进行分离纯化,根据理化性质和核磁共振谱数据鉴定其结构.结果 从牛白藤提取物中分离鉴定了8个化合物:β-谷甾醇(1)、△5.22豆甾醇(2)、莨菪亭(3)、羽扇豆醇(4)、表白桦脂酸(5)、熊果酸(6)、齐墩果酸(7)和咖啡酸(8).结论 化合物4、7和8...
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| 关 键 词： | 牛白膝 化学成分 结构鉴定 |
Studies on the anti-inflammatory chemical constituents of Hedyotis hedyotidea(DC.)Merr. |
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| TAO Shu-hong,CHEN Yan-fen,LI Zhong,YANG Chao-yan,YAN You-shao,WU Yan-wen,XU Pei-ting.Studies on the anti-inflammatory chemical constituents of Hedyotis hedyotidea(DC.)Merr.[J].Academic Journal of Guangdong College of Pharmacy,2011,27(4):364-366. |
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| Authors: | TAO Shu-hong CHEN Yan-fen LI Zhong YANG Chao-yan YAN You-shao WU Yan-wen XU Pei-ting |
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| Institution: | (School of Traditional Chinese Medicine,Guangdong Pharmaceutical University,Guangzhou 510006,China) |
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| Abstract: | Objective To study the anti-inflammatory chemical constituents of Hedyotis hedyotidea.Methods The compounds were isolated and purified by repeated silica column chromatography and identified by their physical characteristics and nuclear magnetic resonance spectrum.Results Eight compounds were isolated and identified as β-sitosterol（1）,Δ5,22stigmasterol（2）,scopoletin（3）,lupeol（4）,3-epi-betulic acid（5）,ursolic acid（6）,oleanolic acid（7） and caffeic acid（8）. Conclusion Compounds 4,7 and 8 were isolated from Hedyotis hedyotidea for the first time. |
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| Keywords: | Hedyotis hedyotidea chemical constituents structure identification |
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