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Pediatric otolaryngologic manifestations of bleeding disorders
Authors:Gino Marioni  Cosimo de Filippis
Institution:1. Department of Neurosciences, Otolaryngology Section, University of Padova, Padova, Italy;2. Department of Neurosciences, Otolaryngology Section, Treviso Branch, University of Padova, Treviso, Italy;3. Department of Medicine DIMED, University of Padova, Padova, Italy;1. Department of Neurosciences, Otolaryngology Section, University of Padova, Padova, Italy;2. Department of Medicine DIMED, University of Padova, Padova, Italy;3. Department of Molecular Medicine, University of Padova, Padova, Italy;1. Department of Neurosciences, Otolaryngology Section, University of Padova, Padova, Italy;2. Department of Neurosciences, Otolaryngology Section Treviso Branch, University of Padova, Treviso, Italy;3. Department of Medicine, DIMED, University of Padova, Padova, Italy;1. Department of Neurosciences, Otolaryngology Section, University of Padova, Padova, Italy;2. Department of Neurosciences, Otolaryngology Section, Treviso Hospital Branch, University of Padova, Treviso, Italy;3. Department of Histology, Microbiology and Medical Biotechnology, Microbiology Section, University of Padova, Padova, Italy;1. Bachelor of Science in Biology, The George Washington University, School of Medicine and Health Sciences, 2300 I St NW, Washington DC;2. Division of Otolaryngology, Children’s National Medical Center, 111 Michigan Ave NW, Washington, DC;3. Department of Dermatology, Penn State Hershey Dermatology, 500 University Drive, UPC 1, Suite 100, Hershey, PA;1. Department of Neurosciences DNS, Otolaryngology Section, Padova University, Padova, Italy;2. Anatomic Pathology Unit, Ospedali Riuniti Bergamo, Bergamo, Italy;3. Department of Medicine DIMED, University of Padova, Italy
Abstract:ObjectiveIn 1930, considering the diseases of the blood and lymphatic glands in relation to otolaryngology, Goldsmith and McGregor stated that “… the otolaryngologist has frequently to deal with bleeding from the nose and throat …”. After approximately 8 decades, in particular preoperatively, the use of universal coagulation screening in children is still controversial. Aim of the present review was to offer a concise but complete discussion of clotting disorders with pediatric otolaryngological interest recognizing: (i) vascular disorders, (ii) platelet disorders, (iii) disorders of coagulation, and (iv) thrombosis.MethodsAn exhaustive review of literature was performed to investigate available data and evidences regarding pediatric otolaryngologic manifestations of bleeding disorders.Results/ConclusionsModern otolaryngologists should be familiar with common bleeding disorders since many have head and neck manifestations. This knowledge allows the choice of appropriate pre-operative screening of surgical patients. The most important component of the preoperative assessment is the bleeding history that directs further laboratory evaluation. All otolaryngologic surgical procedures in children with bleeding disorders should be carried out with the close co-operation of the Haematology Department.
Keywords:
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