聚维酮碘膀胱灌注治疗真菌性尿路感染7例报道

目的 探讨真菌性尿路感染的临床特点及聚维酮碘膀胱灌注治疗真菌性尿路感染的有效性和安全性.方法 7例真菌性尿路感染均长期留置导尿管或膀胱造瘘管;对7例真菌性尿路感染采用0.25％聚维碘酮溶液膀胱灌注,保留5～8 min,观察尿中真菌清除情况.结果 7例尿路真菌感染均得到控制,尿液真菌培养阴性,尿中白细胞消失;1例灌注3d后出现下腹部针刺样疼痛,但可耐受.结论 长期留置尿管和机体抵抗力下降,是引起真菌性尿路感染的重要因素,聚维酮碘膀胱灌注治疗真菌性尿路感染安全、有效.

Intravesical instillation with povidone-iodine for treatment of fungal urinary tract infections

OBJECTIVE To explore the clinical features of fungal urinary tract infection and the efficacy and safety of intravesical instillation with povidone-iodine for the treatment of fungal urinary tract infections.METHODS A total of 7 patients with indwelling catheter or bladder fistula for long term suffering fungal urinary tract infections were enrolled in the study.All the patients were irrigated bladder with 0.25% povidone-iodine solution for 5 to 8 min,then the clearance of fungi in the urine was observed.RESULTS All the 7 patients with urinary tract infections were under control,the urine culture for fungi showed negative,WBC in the urine disappeared;there was only one patient who felt slight lower abdominal pain 3d after the intravesical instillation and can be tolerated.CONCLUSION Long-term indwelling catheter and the decline in body immunity are the main factors for fungal urinary tract infections.Intravesical instillation with povidone-iodine for the treatment of fungal urinary tract infections is safe and effective.