2009-2010年住院患者使用抗菌药物的目标性监测与分析

目的了解使用抗菌药物的具体情况,为合理使用抗菌药物提供管理依据。方法选择2009-2010年出院病例,每月随机抽查各科室当月约10.0%的出院病历,对抗菌药物应用及治疗用药病原学检查情况进行监测。结果两年共监测出院病历5782份,使用抗菌药物4347例,抗菌药物使用率75.2%,联合用药:单用3497例,占80.5%,二联用药804例,占18.5%,≥三联用药44例,占1.0%,特殊用药92例,使用率为2.1%;4347例使用抗菌药物的病历中,治疗用药1873例,占43.1%,预防用药1893例,占43.5%,治疗+预防例581例,占13.4%;治疗用药病原学检查1331例,送检率为54.2%,特殊用药92例,特殊用药病原学检查90例,送检率为97.8%。结论抗菌药物使用率处于较高的水平,治疗用药病原学检查得到进一步改善;应加强管理力度,促进抗菌药物的合理应用。

Targeted monitoring and analysis of antibiotics usage in inpatients during 2009-2010

OBJECTIVE To understand the details of antibiotics usage,so as to provide reference information for management of antibiotics use.METHODS Approximaty 10% of the total discharged patients from each department every month during 2009-2011 were and chosen use of antibiotics as well as etiological examination results were monitered for therapeutic purpose.RESULTS A total of 5782 discharged patients were monitored in the 2 years,of which antibiotics were used in 4347 cases with the antibiotics usage rate of 75.2%.Regarding combination drug regimen,single drug was used in 3497 cases(80.5%),two-drug combination in 804 cases(18.5%),three or more drugs combination in 44 cases(1.0%),and special drug in 92 cases(2.1%).Of the 4347 antibiotic use cases,1873 were for treatment purposes(43.1%),1893 for preventive purposes(43.5%),and 581 for both treatment and preventive purposes(13.4%).Etiological examinations for drug treatment were carried out in 1331 cases(54.2%),special drug use was applied in 92 cases and etiological examinations for special drug use were carried out in 90 cases(97.8%).CONCLUSION The antibiotic use rate remains high,and etiological examinations for therapeutic purpose have been further improved.The results also suggest that monitoring should be performed in a long term basis and management should be strengthened in order to promote the proper use of antibiotics.