支原体属感染与女性继发性不孕的相关性调查

目的 探讨支原体属感染与女性继发性不孕的关系,进一步研究不同种属支原体与女性继发性不孕相关性差异.方法 随机选取2010年1月-2011年6月医院妇科病房收治的继发性不孕患者96例做为观察组；同期来医院行健康体检的103例女性作为对照组,就两组支原体属检出率及计数进行比较并行分析.结果 观察组支原体属感染检测解脲脲支原体(Uu)、人支原体(Mh)、Uu+ Mh阳性率分别为64.6％、21.8％、16.7％,明显高于对照组的12.6％、8.7％、5.8％,两者比较,差异有统计学意义(P＜0.05)；观察组Uu计数＞104 CFU的为49例,与对照组的8例比较,差异有统计学意义(P＜0.05)；输卵管性不孕组Uu阳性率高于非输卵管性不孕组,两者比较,差异有统计学意义(P＜0.05),输卵管性不孕组和非输卵管性不孕组的Mh阳性率差异无统计学意义.结论 支原体属感染与女性继发性不孕关系密切,Uu是女性继发性不孕主要致病支原体属.

Correlation between Mycoplasmainfection and female secondary infertility

OBJECTIVE To study the relationship between Mycoplasma infection and female secondary infertility,and further evaluate difference in correlation between different species of Mycoplasma and female secondary infertility.METHODS All subjects were randomly selected from gynecological wards from Jan 2010 to Jun 2011.96 cases with secondary infertility were set as the observation group;103 patients who received physical examination in our hospital in the same period were selected as the control group.The detection rates and the counts of Mycoplasma in the two groups were compared and analyzed.RESULTS The positive rates of Ureaplasma urealyticum(Uu),Mycoplasma hominis(Mh) and Uu+Mh in observation group were 64.6%,21.8%,and 16.7% respectively,which were significantly higher than in control group(12.6%,8.7%,and 5.8%)(P<0.05).49 cases in observation group showed Uu count >104 CFU.Compared with 8 cases in control group,the difference was statistically significant(P<0.05).Uu positive rate in tubal infertility group was significant higher than non-tubal infertility group(P<0.05).There was no significant difference in Mh positive rate between tubal and non-tubal infertility groups.CONCLUSION It is suggested that the secondary infertility in women is closely correlated with Mycoplasma infection.Uu is the main Mycoplasma species that causes secondary infertility in women.