介入手术预防性使用抗菌药物的调查分析

目的 调查介入手术患者围手术期预防性使用抗菌药物情况,分析存在问题.方法 回顾性调查医院3月份介入手术患者抗菌药物使用情况.结果 198例介入手术患者中,164例预防性使用了抗菌药物,使用率为82.8％,其中单联用药160例,占97.6％,二联用药4例,占 2.4％;使用时间为0～14 d,平均3.02 d；使用频率排名前5位的依次是:头孢尼西、头孢美唑、头孢孟多、青霉素、头孢替唑;手术前2h开始用药的病例8例,占4.9％,术后开始用药156例,占95.1％.结论 介入手术患者抗菌药物预防性使用存在使用率偏高、用药时机不合理、疗程过长等不合理现象,需进一步规范管理,加强培训,加大干预力度,促进抗菌药物合理使用.

Investigation and analysis of prophylactic antibiotics for patients undergoing intervention surgery

OBJECTIVE To investigate the perioperative use of antibiotics in patients undergoing intervention surgery,and analyze the existing problems.METHODS Retrospective analysis was performed to investigate the use of perioperative antibiotics in patients undergoing intervention surgery in Mar 2011.RESULTS Totally 164(82.8%) patients from 198 cases of intervention surgery used antibiotics during perioperative period,including 160 cases(97.6%) for one-drug use,and 4 cases(2.4%) for two-drug;the medication time ranged from 0 to 14 days,the top average time was 3.02 days;the top five antibiotics applied were: cefonicid,cefmetazole,cefamandole,penicillin,ceftezole;8 cases used antibiotics 2h before operation(4.9%),156 cases(95.1%) after operation.CONCLUSION There are many problems existing in the use of perioperative antibiotics in patients undergoing intervention surgery,such as high percent of antibiotics usage,long administration time,unreasonable administration chance.Enhancing the training and stressing on the intervention are important to improve the rational use of antibiotics.