| 宽叶大戟化学成分的研究 |
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| 引用本文： | 邹忠杰,龚梦鹃. 宽叶大戟化学成分的研究[J]. 广东药学院学报, 2010, 26(2): 138-140. DOI: 10.3969/j.issn.1006-8783.2010.02.008 |
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| 作者姓名： | 邹忠杰 龚梦鹃 |
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| 作者单位： | 广东药学院,中药学院,广东,广州,510006;广东药学院,中药学院,广东,广州,510006 |
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| 基金项目： | 广东药学院引进人才科研基金 |
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| 摘 要： | 目的研究宽叶大戟的化学成分。方法采用硅胶柱层析法、Sephadex LH-20凝胶柱层析法,对宽叶大戟全草体积分数95%乙醇提取物的氯仿萃取部分进行分离,根据理化性质和波谱数据确定各化合物的结构。结果分离并鉴定了8个化合物,分别为：三十二烷酸（1）、蒲公英醇（2）、α-波甾醇（3）、羽扇豆醇（4）、β-谷甾醇（5）、白桦酸（6）、齐墩果酸（7）和桦木醇（8）。结论化合物1-4为首次从宽叶大戟中分离得到。
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| 关 键 词： | 宽叶大戟 化学成分 提取 分离 结构鉴定 |
Studies on the chemical constituents from Euphorbia latifolia |
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| ZOU Zhong-jie,GONG Meng-juan. Studies on the chemical constituents from Euphorbia latifolia[J]. Academic Journal of Guangdong College of Pharmacy, 2010, 26(2): 138-140. DOI: 10.3969/j.issn.1006-8783.2010.02.008 |
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| Authors: | ZOU Zhong-jie GONG Meng-juan |
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| Affiliation: | (School of TCM,Guangdong Pharmaceutical College,Guangzhou,Guangdong 510006,China) |
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| Abstract: | Objective To investigate the chemical constituents from Euphorbia latifolia.Methods The constituents of CHCl3-soluble portion of 95% ethanol extract were isolated and purified by repeated chromatographies with silica and Sephadex LH-20.Compounds were identified by their physical characteristics and spectral features.Results Eight compounds were isolated and identified respectively as lacceroic acid（1）,taraxasterol（2）,α-spinasterol（3）,lupeol（4）,β-sitosterol（5）,betulinic acid（6）,oleanolic acid（7） and betulin（8）.Conclusion Compounds 1-4 were isolated from this plant for the first time. |
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| Keywords: | Euphorbia latifolia chemical constituents extraction isolation structural identification |
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