| 加味保安方对鸡胚尿囊膜血管新生的影响 |
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| 引用本文： | 李晓丽,王世军.加味保安方对鸡胚尿囊膜血管新生的影响[J].中国微循环,2005,9(4):248-250. |
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| 作者姓名： | 李晓丽 王世军 |
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| 作者单位： | 250014,山东济南,山东中医药大学 |
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| 基金项目： | 山东省中医药管理局资助课题(编号2004-08) |
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| 摘 要： | 目的观察加味保安方对鸡胚尿囊膜血管(CAM)生成的影响。方法采用血清药理学方法制备含药血清。观察含药血清对培养5、6、7dCAM血管生成的影响,并与生理盐水及正常血清组对照。结果加味保安方含药血清可抑制鸡胚CAM血管生成。其中对培养5dCAM血管生成的抑制作用与生理盐水组比较差异具显著性(P<0.05);对培养6dCAM的作用,仅大剂量组与生理盐水组比较差异具显著性(P<0.05);对培养7dCAM的作用最为显著,与生理盐水组及正常血清组比较差异均具显著性(P<0.05)。结论加味保安方具有抑制鸡胚尿囊膜血管生成的作用。
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| 关 键 词： | 加味保安方 鸡胚尿囊膜 血管生成 |
| 文章编号： | 1007-8568(2005)04-0248-03 |
| 修稿时间： | 2004年11月3日 |
The Influence of the Formula of Jia Wei Bao An on Angiogenesis in Chicken Embryo Allantois Membrane |
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| LI Xiao-li,WANG Shi-jun.The Influence of the Formula of Jia Wei Bao An on Angiogenesis in Chicken Embryo Allantois Membrane[J].Journal of Chinese Microcirculation,2005,9(4):248-250. |
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| Authors: | LI Xiao-li WANG Shi-jun |
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| Institution: | LI Xiao-li,WANG Shi-jun. Shandong University of TCM,Jinan 250014 China |
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| Abstract: | Objective To observe the influence of the Formula of Jia Wei Bao An on angiogenesis in chicken embryo allantois membrane (CAM). Method The drug-contained serum was prepared using serum-pharmacological method. Chicken embryos were hatched for five, six and seven days, and then angiogenesis in CAM was observed after application of drug-contained serum, normal serum and saline. Result The drug-contained serum showed anti-angiogenesis effects on CAM. The effects on CAM hatched for five days were evident compared with the effects in saline group(P<0.05). The effects on CAM hatched for six days were evident in high dosage compared with the effects in saline group(P<0.05). The effects on CAM hatched for seven days were the most evident compared with the effects in both saline group and normal serum group(P<0.05). Conclusion The Formula of Jia Wei Bao An possesses anti-angiogenesis effect on CAM. |
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| Keywords: | The formula of Jia Wei Bao An CAM Angiogenesis |
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