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七味都气丸对小鼠记忆能力及抗氧化能力的影响
引用本文:张春蕾,张丹丹.七味都气丸对小鼠记忆能力及抗氧化能力的影响[J].贵阳医学院学报,2011,0(4):355-358.
作者姓名:张春蕾  张丹丹
作者单位:黑龙江中医药大学佳木斯学院,黑龙江佳木斯,154007
摘    要:目的:研究七味都气丸对D-半乳糖致衰小鼠记忆力、抗氧化能力的影响。方法:将小鼠随机分为6组,每组10只,正常对照组(Ⅰ)、模型对照组(Ⅱ)、维生素E组(Ⅲ)、七味都气丸低剂量组(Ⅳ)、七味都气丸中剂量组(V)、七味都气丸高剂量组(Ⅵ),除正常对照组外其余各组用D-半乳糖制造衰老模型,再分别给予维生素E和不同浓度的七味都...

关 键 词:七味都气丸  乙酰胆碱酯酶  超氧化物歧化酶  小鼠  学习记忆

Effects of Qiweiduqi Pill on Memory Ability,Serum Superoxide Dismutase and Brain Acetylcholinesterase Activities of Rats
ZHANG Chunlei,ZHANG Dandan.Effects of Qiweiduqi Pill on Memory Ability,Serum Superoxide Dismutase and Brain Acetylcholinesterase Activities of Rats[J].Journal of Guiyang Medical College,2011,0(4):355-358.
Authors:ZHANG Chunlei  ZHANG Dandan
Institution:ZHANG Chunlei,ZHANG Dandan (Jiamusi College,Traditional Chinese Medicine University of Heilongjiang,Jiamusi 154007,Heilongjiang,China)
Abstract:Objective:To study the effects of Qiweiduqi pill(QWDQP) on memory and anti-oxidation abilities of aging rats caused by D-gal.Methods:Rats were randomly divided into 6 groups with 10 in each group:normal control group(Ⅰ),model group(Ⅱ),vitamin E group(Ⅲ) and groups of low,moderate,high doses of QWDQP(groups Ⅳ,Ⅴ,and Ⅵ).Ageing models were established using D-glucose with rats in all the groups except groupⅠ,and then were given vitamin E or different doses of QWDQP respectively.Memory ability,serum superoxide dismutase(SOD) and brain acetylcholinesterase(AchE) activities of rats were detected.Results:QFDQP could improve escaping ability of aging rats stimulated by electricity and could also improve activities of serum SOD and brain AchE.Conclusion:QWDQP can improve memory ability of aging rats and is effective in clearing free radicals.So QWDQP makes physiological function better apparently and acts anti-aging function.
Keywords:Qiweiduqi pill  acetylcholinesterase  superoxide dismutase  mice  learning and memory  
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