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石菖蒲配伍冰片对缺血再灌注脑损伤大鼠内皮素的影响
引用本文:王淑英,吴启端,李翎,魏刚,林双峰,方永奇. 石菖蒲配伍冰片对缺血再灌注脑损伤大鼠内皮素的影响[J]. 时珍国医国药, 2003, 14(4): 199-200
作者姓名:王淑英  吴启端  李翎  魏刚  林双峰  方永奇
作者单位:广州中医药大学第一附属医院实验中心,广东,广州,510405
摘    要:目的:探讨石菖蒲配伍冰片对大鼠抉血再灌注脑损伤内皮素的影响。方法:大鼠灌胃给药7d,造成脑缺血再灌注损伤模型,采用放射免疫法制定血浆和脑组织内皮素含量。结果:石菖蒲配伍冰片高、中剂量组脑组织内皮素含量明显下降,并显量效关系。结论:石菖蒲配伍冰片能够降低脑缺血再灌注大鼠脑组织中内皮素含量,发挥护脑醒脑之功效。

关 键 词:石菖蒲 冰片 内皮素 配伍 缺血再灌注脑损伤 放射免疫法 脑缺血
文章编号:1008-0805(2003)04-0199-01
修稿时间:2002-08-20

Effects of Acorus tatarinowii Schott Used Together with Bornelo on Endothelin in the Rats Undergone Cerebral Ischemia and Reperfusion
WANG Shu ying,WU Qi duan,LI Ling,WEI Gang,LIN Shuang feng,FANG Yong qi. Effects of Acorus tatarinowii Schott Used Together with Bornelo on Endothelin in the Rats Undergone Cerebral Ischemia and Reperfusion[J]. Lishizhen Medicine and Materia Medica Research, 2003, 14(4): 199-200
Authors:WANG Shu ying  WU Qi duan  LI Ling  WEI Gang  LIN Shuang feng  FANG Yong qi
Abstract:Objective:To observe effects of Acorus tatarinowii Schott used together with borneol on endothelin in the rats undergone cerebral ischemia and reperfusion. Methods: Give Acorus tatarinowii Schott together with borneol for 7 days by op, then made the rat model of undergone cerebral ischemia and reperfusion. The level of endothelin detected by radioimmunoassay. Results: It was found that the level of endothelin obviously lower when Acorus tatarinowii Schott used together with borneol. Conclusion: Acorus tatarinowii Schott used together with borneol can protect the rats undergone cerebral ischemia and reperfusion.
Keywords:Acorus tatarinowii Schott  Borneol  Cerebral ischemia  Endothelin
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