| 补益阳明津气对初老雌性大鼠卵巢门血管影响的实验研究 |
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| 引用本文： | 李燕,王毅,郭蓉晓,周淑芳,谭万信.补益阳明津气对初老雌性大鼠卵巢门血管影响的实验研究[J].上海中医药杂志,2009,43(4):77-79. |
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| 作者姓名： | 李燕 王毅 郭蓉晓 周淑芳 谭万信 |
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| 作者单位： | 李燕,LI Yan(贵阳中医学院,贵州,贵阳,550002);王毅,郭蓉晓,WANG Yi,GUO Rong-xiao(成都中医药大学附属医院病理科,四川,成都,610075);周淑芳,谭万信,ZHOU Shu-fang,TAN Wan-xin(成都中医药大学,四川,成都,610075)
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| 摘 要： | 目的探讨“补益阳明津气”对初老雌性大鼠卵巢门血管的影响，并以此佐证中医传统经典理论“五七，阳明脉衰”在绝经前期生殖轴机能衰老中的重要影响。为促进绝经前期妇女健康、延缓绝经前期卵巢机能衰老、防治相关病症提供一种新的研究与论治思路，并为研制相关方药提供药效学依据。方法4-6月龄雌性大鼠为正常对照组；10—12月龄，阴道细胞学表现动情期延长的雌性大鼠作为初老大鼠模型。模型动物随机分为益胃汤高剂量组、益胃汤中剂量组、益胃汤低剂量组、己烯雌酚组、模型对照组和六味地黄丸组。灌药4周后，断头处死，取左侧卵巢用于检测卵巢门血管。结果与模型对照组比较，益胃汤高、中剂量组卵巢门血管壁变薄，管腔扩大，卵巢血供增加。结论实验研究提示益胃汤具有改善卵巢局部血供的作用，这可能是其延缓卵巢机能衰老的机制之一。
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| 关 键 词： | 补益阳明津气 动物实验 初老雌性大鼠 卵巢门血管 |
Effects of "Tonifying Yangming Fluid and Qi" on Hilus Vessel of Ovary in Presenile Female Rats |
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| LI Yan WANG Yi GUO Rong-xiao ZHOU Shu-fang TAN Wan-xin.Guiyang College of Traditional Chinese Medicine.Effects of "Tonifying Yangming Fluid and Qi" on Hilus Vessel of Ovary in Presenile Female Rats[J].Shanghai Journal of Traditional Chinese Medicine,2009,43(4):77-79. |
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| Authors: | LI Yan WANG Yi GUO Rong-xiao ZHOU Shu-fang TAN Wan-xinGuiyang College of Traditional Chinese Medicine |
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| Institution: | LI Yan1 WANG Yi2 GUO Rong-xiao2 ZHOU Shu-fang3 TAN Wan-xin31.Guiyang College of Traditional Chinese Medicine2. Affiliated Hospital of Chengdu University of Traditional Chinese Medicine3. Chengdu University of Traditional Chinese Medicine |
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| Abstract: | Objective To study the effects of "Tonifying Yangming Fluid and Qi" on the hilus vessel of ovary in presenile rats and verify the Chinese medical theory that "Yangming meridian declines in the fifth seven-year period" in premenopause. Methods Four to six months old SD female rats were enrolled in control group,and 10~12 months old SD female rats with oestrus elongation in model group. Presenile female rats were devided into 6 groups:high-dose "Yiwei Decoction" group(Group A),middle-dose "Yiwei Decoction" gr... |
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| Keywords: | Tonifying Yangming Fluid and Qi animal experiment presenile female rat hilus vessel of ovary |
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