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Overexpression of JAZF1 protected ApoE-deficient mice from atherosclerosis by inhibiting hepatic cholesterol synthesis via CREB-dependent mechanisms
Authors:Xiaoqiang Li  Mengliu Yang  Han Wang  Yanjun Jia  Pijun Yan  Guenther Boden  Gangyi Yang  Ling Li
Affiliation:1. The Key Laboratory of Laboratory Medical Diagnostics in the Ministry of Education and Department of Clinical Biochemistry, College of Laboratory Medicine, Chongqing Medical University, 400016 Chongqing, China;2. Department of Endocrinology, the Second Affiliated Hospital, Chongqing Medical University, 400010 Chongqing, China;3. The Division of Endocrinology/Diabetes/Metabolism and the Clinical Research Center, Temple University School of Medicine, Philadelphia, PA, USA
Abstract:
Keywords:TAK1/TR4, nuclear receptor subfamily 2, group C, member 2   EHC, euglycemic&ndash  hyperinsulinemic clamp   HFD, high fat diet   CREB, cAMP response element-binding protein   HMGCR, 3-hydroxy-3methylglutaryl coenzyme A reductase
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