| 丙溴磷对人红细胞膜的毒性作用 |
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| 引用本文： | 刘希英, 吕锐. 丙溴磷对人红细胞膜的毒性作用[J]. 中国公共卫生, 2000, 16(9): 786-787. DOI: 10.11847/zgggws2000-16-09-08 |
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| 作者姓名： | 刘希英 吕锐 |
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| 作者单位： | 1.青岛大学医学院 青岛266021 |
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| 摘 要： | 为探讨丙溴磷对人红细胞膜的毒性作用,检测了红细胞膜Ⅰ型补体受体(Em-CR1)免疫粘附肿瘤细胞活性与红细胞超氧化物歧化酶(E-SOD)活性、红细胞膜唾液酸(Em-SA)含量以及红细胞膜脂流动性.结果发现,一定浓度丙溴磷可使上述各项指标显着降低,并呈现剂量-效应关系,提示丙溴磷对人红细胞膜有明显的毒性作用
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| 关 键 词： | 丙溴磷 人红细胞 Ⅰ型补体受体 唾液酸 超氧化物岐化酶 膜脂流动性 |
| 收稿时间： | 2000-01-31 |
| 修稿时间： | 2000-01-31 |
The Noxious Effects of Profenofos on Human Erythrocyte Membrane |
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| Liu Xiying, . The Noxious Effects of Profenofos on Human Erythrocyte Membrane[J]. Chinese Journal of Public Health, 2000, 16(9): 786-787. DOI: 10.11847/zgggws2000-16-09-08 |
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| Authors: | Liu Xiying |
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| Affiliation: | 1.Qingdao Univercity Medical College, Qingdao 266021 |
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| Abstract: | In order to study the noxious effects of profenofos on human erythrocyte membrane,the activity of erythrocyte membrane complement receptor type 1(Em-CR1)and erythrocyte superoxide dismutase(E-SOD),the level of erythrocyte membrane sailic acid(Em-SA) and erythrocyte membrane lipid fluidity were determined.The results showed that certain concentration of profenofos may obviously decrease above-mentioned indices and appear the relationship of dose-effect.It prompted that Profenofos has a obvious toxicity on human erythrocyte membrane. |
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| Keywords: | Profenofos Human erythrocyte complement receptor type 1 Sailic acid Superoxide dismutase Membrane lipid fluidity |
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