| 系统性红斑狼疮患者外周血T淋巴细胞亚群的变化 |
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| 引用本文： | 许坤,张永亮,张敬然.系统性红斑狼疮患者外周血T淋巴细胞亚群的变化[J].实用医技杂志,2007,14(29):3991-3992. |
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| 作者姓名： | 许坤 张永亮 张敬然 |
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| 作者单位： | 解放军第251医院,河北,张家口,075000 |
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| 摘 要： | 目的:研究系统性红斑狼疮(SLE)患者外周血T淋巴细胞亚群变化及其临床意义。方法:对30例患者和20例健康者,采用特异性荧光抗体标记,流式细胞检测T淋巴细胞亚群的变化。结果:SLE活动组CD4+细胞数明显降低(P<0.05);CD4+/CD8+比值明显降低(P<0.05)。结论:T淋巴细胞亚群在SLE的发病机制中起重要作用。
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| 关 键 词： | 系统性红斑狼疮 T淋巴细胞亚群 流式细胞术 |
| 文章编号： | 1671-5098（2007）29-3991-02 |
| 收稿时间： | 2007-07-14 |
The Change of Peripheral Blood T Lymphocyte Subsets in Patients with Different Clinical Types of Systemic Lupus Erythematosus |
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| XU Kun,ZHANG Yong-liang,ZHANG Jing-ran.The Change of Peripheral Blood T Lymphocyte Subsets in Patients with Different Clinical Types of Systemic Lupus Erythematosus[J].Journal of Practical Medical Techniques,2007,14(29):3991-3992. |
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| Authors: | XU Kun ZHANG Yong-liang ZHANG Jing-ran |
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| Institution: | No, 251 Hospital of PLA, Zhangjiakou, Hebei 075000, China |
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| Abstract: | Objective To study the change of T lymhocyte subsets with systemic lupus erythematosus.Methods 30 patients with systemic lupus erythematosus and 20 cases of healthy subjects were investigated and the change of T Lymphocyte subsets were counted by flow cytometer.Results Decrease in CD4+ cells and was observed in SLE patients(P<0.05).Conclusion T lymphocyte isplay an important role in the development of SLE. |
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| Keywords: | Systemic lupus erythematosus T lymphocyte Flow cytomety |
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