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Singularities of nevirapine metabolism: from sex-dependent differences to idiosyncratic toxicity |
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| Authors: | Aline T Marinho Joana P Miranda Umbelina Caixas Catarina Charneira Clara Gonçalves-Dias M Matilde Marques |
| Institution: | 1. CEDOC, Chronic Diseases Research Centre, NOVA Medical School/Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, Lisboa, Portugal;2. Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisboa, Portugal;3. Centro Hospitalar de Lisboa Central (CHLC), Lisboa, Portugal;4. Centro de Química Estrutural (CQE), Instituto Superior Técnico, ULisboa, Lisboa, Portugal |
| Abstract: | |
| Keywords: | Nevirapine bioactivation protein adducts sulfotransferases hepatotoxicity sex-dependent differences drug metabolism adverse drug reactions pharmacogenetics |