艾滋病合并肺孢子菌肺炎88例临床研究

目的 探讨AIDS合并肺孢子菌肺炎(PCP)患者临床特点及其与预后相关的因素.方法 采用回顾性研究方法分析我院88例AIDS合并PCP患者的一般资料、感染途径、血气分析、血常规、血清清蛋白、血乳酸脱氢酶、治疗和转归情况等临床资料.按照PaO_2水平将88例AIDS患者分为轻度异常组(PaO_2＞70 mm Hg),中度异常组(50 mm Hg≤PaO_2≤70 mm Hg)和重度异常组(PaO_2＜50 mm Hg)3组,比较3组的一般资料和实验室检查结果,分析影响预后的因素.结果 3组患者的血清清蛋白水平、死亡率比较差异有统计学意义(P＜0.05).存活患者与死亡患者两组比较,PaO_2和SaO_2下降以及是否需要呼吸机呼吸支持两组间差异有统计学意义(P＜0.05).结论 PaO_2、血清清蛋白水平下降是发现AIDS合并PCP患者病情加重和预后不良的指标,治疗中应予重视并尽早给氧和营养支持治疗.

AIDS Complicated by Pneumocystis Jirovecii Pneumonia:A clinical study of 88 cases

Objective To investigate the clinical characteristics and correlative factors with prognosis in AIDS patients complicated by Pneumocystis jirovecii pneumonia (PCP).Methods The data of 88 adults AIDS patients with PCP were retrospectively analyzed,including general data,and such clinical data as routes of HIV infection,blood gas analysis,blood routine,serum albumin,serum lactate dehydrogenase,therapeutic managements and clinical outcomes.The patients were divided according to the levels of their PaO2 as mild...