广西九里香化学成分研究

目的　对广西九里香(Murraya kwangsiensis)的化学成分进行研究。方法　利用硅胶柱色谱和薄层色谱方法对广西九里香的95%乙醇提取物进行分离；采用UV,IR,MS,¹HNMR和¹³CNMR等技术对所得化合物进行结构研究。结果　分离鉴定了7个化合物，其中5个为咔巴唑生物碱:murrayafoline-A,murrayanine,koenine,isomahanine和广西九里香碱(kwangsine),两个非生物碱化合物：棕榈酸和β-谷甾醇。结论　广西九里香碱(kwangsine)为新化合物，其他化合物均为首次从该植物中分离得到。

STUDIES ON THE CHEMICAL CONSTITUENTS OF MURRAYA KWANGSIENSIS

AIM: To investigate the chemical constituents of Murraya kwangsiensis. METHODS: Compounds were isolated by silica gel column chromatography and TLC method, respectively. Structures of compounds were elucidated by spectral (UV, IR, MS, 1HNMR and 13CNMR) analysis. RESULTS: Five carbazole alkaloids and two other compounds were isolated and identified. Six of them are known compounds: murrayafoline A, murrayanine, koenine, isomahanine, palmitic acid and beta-sitosterol. One is a new alkaloid, named kwangsine. CONCLUSION: A new alkaloid, named kwangsine, was isolated from Murraya kwangsiensis Var. Six known compounds were isolated from this plant for the first time.