消化系统癌肿病人血清T_3、T_4变化及其临床意义

测定76例消化系统癌肿病人的血清T_3、T_4浓度.与正常对照组和良性疾病组比较,发现T_3明显降低,T_4无显著性变化.不同种类消化系统癌肿(胃癌、大肠癌、原发性肝癌、胰腺癌)病人之间血清T_3、T_4从浓度元显著性差异.将病人依据手术和病理结果分为轻、中、重三组比较,发现病变程度与血清T_3水平有关,病变越严重,T_3浓度越低.结果表明,消化系统癌肿病人可出现低T_3综合征,T_3可作为估计病变程度和能否根治性切除的指标.

CHANGES OF SERUM T_3 AND T_4 IN PATIENTS WITH CANCERS OF DIGESTIVE SYSTEM

Serum T3,T4 contents were measured in 76 patients with cancers of digestive system, including 45 gastric cancers,20 large intestinal cancers,5 primary liver cancers,5 pancreatic cancers and 1 small intestinal cancer. In comparison with the control groups,T3 was significantly lower and T4 had no changes. The differences in T3,T4 among the kinds of cancers of digestive system were not found. The patients were-divided into three groups according to the operative and pathological findings ,it was found that the magnitude of T3 changes was proportional to the severity of the illness. It is concluded that low T3 syndrome can be found in patients with cancer of digestive system and T3 can be used as an index for evaluating the radical resectability of the tumors.