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呼吸上皮细胞在臭氧气液界面暴露后的氧化损伤效应研究
引用本文:王科霖,管东波,宋宏. 呼吸上皮细胞在臭氧气液界面暴露后的氧化损伤效应研究[J]. 环境与健康杂志, 2011, 0(5): 397-400,封3
作者姓名:王科霖  管东波  宋宏
作者单位:中山大学公共卫生学院;佛山市南海区疾病预防控制中心职业卫生科;
摘    要:目的 探讨臭氧(ozone,O3)对人呼吸上皮细胞(human respiratory epithelial cells,BEAS-2B)的氧化损伤效应及氧化损伤与炎症效应分子分泌的关系.方法 利用完全融合并分化完全的人呼吸上皮细胞及petri-PERM透气培养皿建立臭氧体外暴露系统,设立对照(无菌空气)组和高(0.5...

关 键 词:臭氧  气液界面  人呼吸上皮细胞  氧化损伤

Oxidative Damage Effect in Respiratory Epithelial Cells Induced by Exposure to Ozone in Air-Liquid Interface
WANG Ke-lin,GUAN Dong-bo,SONG Hong.School of Public Health,Sun Yat-Sen University,Guangzhou,Guangdong ,China. Oxidative Damage Effect in Respiratory Epithelial Cells Induced by Exposure to Ozone in Air-Liquid Interface[J]. Journal of Environment and Health, 2011, 0(5): 397-400,封3
Authors:WANG Ke-lin  GUAN Dong-bo  SONG Hong.School of Public Health  Sun Yat-Sen University  Guangzhou  Guangdong   China
Affiliation:WANG Ke-lin,GUAN Dong-bo,SONG Hong.School of Public Health,Sun Yat-Sen University,Guangzhou,Guangdong 510080,China
Abstract:Objective To investigate the oxidative damage effects of ozone on human respiratory epithelial cells and the relationship between the oxidative damage and the secretion of inflammatory effect molecules.Methods Ozone exposure system in vitro was established with hologamy and completely differentiatted human bronchial epithelial cells and petri-PERM culture dish.Four groups were set:control group(filtrated air),high dose of ozone group(0.50 mg/m3),low dose of ozone group(0.16 mg/m3)and low dose of ozone expos...
Keywords:Ozone  Air-liquid interface  Human respiratory epithelial cells  Oxidative damage  
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