超声造影在肾脏良恶性肿瘤诊断中的价值探讨

目的探讨超声造影再肾脏良恶性肿瘤诊断中的价值。方法选取经阳原县人民医院B超室检查,并行超声引导性穿刺活检或手术取病变组织行病理检查确诊为肾脏占位性病变患者47例,对其行SonoVue超声造影检查,并运用时间-强度曲线分析软件对储存的动态图像进行定量分析。结果恶性病变主要表现为快速增强、快速减退,良性病变主要表现为慢速增强、慢速减退。恶性肿瘤超声造影峰值时间低于良性病变,两者对比差异有统计学意义(P<0.05)。恶性肿瘤超声造影时间-强度曲线中峰值强度、曲线尖度以及曲线下面积均高于良性病变,比较差异有统计学意义(P<0.05)。结论超声造影时间-强度曲线定量分析肾脏占位性病变,有助于肾脏良恶性肿瘤的诊断和鉴别诊断。

Investigation of the Value of Contrast-enhanced Ultrasound in Diagnosis for Benign and Malignant Renal Tumors

Objective To investigate the value of real-time contrast-enhanced ultrasound sonography （CEUS） in the diagnoses of benign and malignant kidney tumors. Methods 47 cases were collected from Department of B-Ultrasound, Yuanyang CountyPeople＇s Hospital. All of them were initially diagnosed as renal tumors by routine ultrasound. The diagnoses were further made clear by puncture biopsy guided by the ultrasound and pathological examination for the tissue obtained from operation. All cases received the check of real-time gray-scale contrast-enhanced sonography with SonoVue. The dynamic pictures taken were quanti- tatively analyzed with the time-intensity curve analysis software. Results The malignant tumor demonstrated a fast enhancement and a rapid decline while benign tumor revealed a slow enhancement and a slow decline. The peak time of contrast-enhanced uitrasonography of malignant tumor was lower than that of benign lesions, the difference has statistical significance（ P 〈 0.05 ）. The intensity of the curve peak, the curve sharpness and the area under the curve of malignant tumor were different from those of benign tumors（ P 〈 0.05 ）. Condusion Quantitative analysis for the dynamic changes with CEUS time-intensity curve is helpful for the diagnosisand differential diagnosis of the renal benign and malignant tumors.