丹参注射液辅助治疗小儿支气管肺炎疗效观察

目的:观察丹参注射液辅助治疗小儿支气管肺炎临床疗效和安全性。方法:选取收治的70例小儿支气管肺炎患儿,随机分为观察组和对照组各35例。对照组采用常规治疗方案,观察组在对照组治疗的基础上,加用丹参注射液。治疗5～7天后,对比两组患儿的临床疗效以及不良反应。结果:治疗5～7天后,观察组的患儿中,治愈18例,总有效率为97.14%,明显高于对照组治愈10例及总有效率85.71%,差异具有统计学意义(P<0.05)。观察组患儿咳嗽停止的平均时间为(4.58±0.62)天,气促消失的平均时间为(3.59±1.18)天,肺部罗音消失的平均时间为(5.84±0.81)天,平均住院天数为(7.34±0.57)天,以上数据均明显少于对照组患儿,差异均有统计学意义(P<0.05)。两组患儿体温恢复时间比较,差异无统计学意义(P>0.05)。两组患儿治疗过程中均未出现严重不良反应。结论:运用丹参注射液辅助治疗小儿支气管肺炎,能够明显提高临床疗效,缩短患儿的住院天数,有效改善患儿临床症状,且安全性高。

The Study of Danshen Injection in Adjuvant Treatment of Infant Bronchial Pneumonia

Objective：To observe the efficacy and safety of danshen injection in adjuvant treatment of infant bronchial pneumonia. Methods：70 children with bronchial pneumonia were selected in our hospital, they were randomly divided into the observation group and the control group with 35 cases in each group. The children in the control group were treated with routine treatment, while the children in the observation group were treated based on the control group, and combined with danshen injection. The effi cacy and adverse reaction in both groups were compared after treated for 5-7 days. Results： 18 children were observed cured, and the total effective rate was 97.14% in the observation group, they were significantly higher than that in the control group with 10 children cured and the total effective rate was 85.71%, the differences were statistically significant （P〈0.05）. The average cough stopping time was （ 4.58 ±0.62） days, the average shortness of breath away time was （3.59±1.18） days, the average pulmonary rales disappear time was （5.84±0.81） days, and the average length of stay time was （7.34±0.57） days in the observation group, all indexes were less than those in the control group, the differences were statistically significant （P〈0.05）. No serious adverse re-action observed in both groups. Conclusion：The use of danshen injection in adjuvant treatment of bronchial pneumonia, can signifi candy improve the clinical efficacy, shorten the clays of hospitalization, effectively improve the clinical symptoms, and improve the security.