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间充质干细胞与炎症性肠病的研究进展
引用本文:左冬梅,寿折星,范恒,刘星星,曹丹,邹舟. 间充质干细胞与炎症性肠病的研究进展[J]. 胃肠病学, 2013, 18(3): 182-184
作者姓名:左冬梅  寿折星  范恒  刘星星  曹丹  邹舟
作者单位:左冬梅 (华中科技大学同济医学院附属协和医院中西医结合科,430022); 寿折星 (华中科技大学同济医学院附属协和医院中西医结合科,430022); 范恒 (华中科技大学同济医学院附属协和医院中西医结合科,430022); 刘星星 (华中科技大学同济医学院附属协和医院中西医结合科,430022);曹丹 (华中科技大学同济医学院附属协和医院中西医结合科,430022);邹舟 (华中科技大学同济医学院附属协和医院中西医结合科,430022);
摘    要:间充质干细胞(MSC)是一种具有多分化潜能的细胞,还具有免疫调节功能。炎症性肠病(IBD)的病因和发病机制目前尚未完全明确,近年研究显示免疫紊乱在IBD的发病中起重要作用。MSC的免疫调节特性为治疗IBD提供了一种潜在的可能性。本文就MSC的免疫调节效应及其在IBD中的作用作一综述。

关 键 词:间质干细胞  免疫调节效应  炎症性肠病  治疗

Advances in Study on Mesenchymal Stem Cells and Inflammatory Bowel Disease
ZUO Dongmei,SHOU Zhexing,FAN Heng,LIU Xingxing,CAO Dan,ZOU Zhou. Advances in Study on Mesenchymal Stem Cells and Inflammatory Bowel Disease[J]. Chinese Journal of Gastroenterology, 2013, 18(3): 182-184
Authors:ZUO Dongmei  SHOU Zhexing  FAN Heng  LIU Xingxing  CAO Dan  ZOU Zhou
Affiliation:.( Department of Integrated Chinese and Western Medicine, Union Hospital, Toni Medical College, Huazhong University of Science and Technology, Wuhan (430022))
Abstract:Mesenchymal stem cells (MSC) are cells with muhipotent differentiation capacity, and also have the property immunomodulation. The etiology and pathogenesis of inflammatory bowel disease (IBD) is not yet fully clarified, many studies have shown that immune disorder plays an important role in the pathogenesis of IBD in recent years. Immunomodulation effect of MSC provides a potential treatment for IBD. This article reviewed the immunomodulation effect of MSC and its role in IBD.
Keywords:Mesenchymal Stem Cells  Immunomodulation Effect  Inflammatory Bowel Disease  Therapy
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