| 兔自体神经原位移植限制创伤性神经瘤形成机理 |
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| 引用本文： | 刘会敏,陈咏莲,叶挺军,臧鸿声. 兔自体神经原位移植限制创伤性神经瘤形成机理[J]. 第二军医大学学报, 1993, 0(1) |
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| 作者姓名： | 刘会敏 陈咏莲 叶挺军 臧鸿声 |
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| 作者单位： | 长征医院病理科 200003(刘会敏，陈咏莲，叶挺军)，长征医院骨科 200003(臧鸿声) |
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| 摘 要： | 本实验采用家兔近端正中神经和尺神经原位移植法研究预防创伤性神经瘤形成之机理。经光镜,透射电镜及免疫组化标记观察表明:(1)自体神经原位移植法能有效地抑制创伤性神经瘤形成。两神经再生的神经纤维在移植段中排列整齐,来自两神经的轴索末端髓鞘对接是抑制创伤性神经瘤形成的关键;(2)移植段中由于雪旺氏细胞增生所形成的雪旺氏鞘对近端神经轴索的再生有趋化和引导作用;(3)单纯吻合法不能抑制创伤性神经瘤的发生。
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| 关 键 词： | 神经瘤 移植 正中神经 尺神经 动物 兔 |
Experimental Study of the Mechanism of Autogenous Nerve Replantation in situ Inhibition of Traumatic Neuroma Formation |
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| Liu Huimin,Chen Yonglian,Ye Tingjun,Zang Hongsheng. Experimental Study of the Mechanism of Autogenous Nerve Replantation in situ Inhibition of Traumatic Neuroma Formation[J]. Former Academic Journal of Second Military Medical University, 1993, 0(1) |
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| Authors: | Liu Huimin Chen Yonglian Ye Tingjun Zang Hongsheng |
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| Abstract: | In this study, two experimental patterns of autogenous nerve replantation in situ and centrocentral nerve simple suture were performed on the rabbit median and ulnar nerves. By light and transmission electron microscopy and immunohistochemistry, the results showed that autogenous nerve replantation in situ could inhibit neuroma formation, and its mechanism might that two proximal stump axons could conjunct within interpolated graft segment, and the nerve simple suture could not inhibit neuroma development for lack of proper environment for conjunction of two proximal stump axons. |
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| Keywords: | neuroma transplantation media and ulnar nerve animal rabbits |
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