健康体检人群脂肪肝与代谢综合征及其组分的关系

目的 探讨健康体检人群中脂肪肝与代谢综合征(MS)及其组分的关系.方法 对江门市2 245名体检人群开展问卷调查、体格检查及实验室检查和腹部B超检查,按是否合并脂肪肝分为脂肪肝组和对照组,比较两组代谢指标的水平、异常率及个数,采用Logistic回归分析脂肪肝与各代谢指标的相关性.结果 2 245名健康体检成人中MS和脂肪肝的检出率分别为15.55％和34.74％,脂肪肝组的体质指数、血压、甘油三酯(TG)、血糖、血尿酸水平均显著高于对照组(P＜0.01),高密度脂蛋白胆固醇( HDL-C)则低于对照组(P＜0.01)；脂肪肝组的肥胖、高血压、糖代谢异常、脂代谢和MS异常率则显著高于对照组(P＜0.01),脂肪肝组的代谢组分检出数显著高于对照组,肥胖、血糖异常、高TG、低HDL-C、高血尿酸等为脂肪肝的独立危险因素.结论 江门市健康体检人群的MS和脂肪肝同为常见病,脂肪肝与多元代谢紊乱关系密切,应对并存多种危险因素的患者给予更多的关注和干预.

Relationship between fatty liver and metabolic syndrome in health examination people

Objective To explore and analyze the relationship between fatty liver and metabolic syndrome.Methods By cluster sampling,2 245 people in Jiangmen city had questionnaire,physical check-up,laboratory examination and abdomen ultrasonic examination.According to the availability of fatty liver,they were divided into fatty liver group and control group.The differences of the two groups were compared for the abnormal rate and the number of metabolic indexes by Logistic regression analysis.Results The detection rate of metabolic syndrome and fatty liver was 15.55% and 34.74%,respectively.The values of body mass index(BMI),blood pressure,triglyceride(TG),blood glucose(BG),and blood uric acid(BUA) of the fatty liver group were much higher than the control group(P <0.01).The level of high-density lipoprotein cholesterol(HDL-C) in the fatty liver group was lower than the control group(P<0.01).The rate of over-weight obesity,high blood pressure,glycometabolism,lipid metabolism and metabolic syndrome of fatty liver group were much higher than the control group(P<0.01).The detection rate of metabolic components in the fatty liver group was much higher than the control group.Conclusions Metabolic syndrome and fatty liver are commonly found during the examination of the population of Jiangmen city.Fatty liver has a close relationship with multivariate metabolic disorder.We should pay more attention to patients with multiple risk factors.