溶栓与抗凝治疗对肺栓塞远期效果评价

目的评价溶栓与抗凝治疗对肺栓塞远期疗效。方法经肺动脉造影或增强螺旋CT证实的急性肺栓塞51例,随机分两组,一组为抗凝组,另一组为静脉或导管内溶栓组,3年后观察血气分析、右室、右房、右室流出道、左室、左房、肺动脉压力。结果两组在血气分析、右室、右房、右室流出道、左室、左房、肺动脉压力测量结果无显著性差异。结论抗凝与溶栓治疗的远期疗效相近,对无血流动力学改变的肺栓塞,抗凝即可获得确切的疗效。

Clinical evaluation of long-term results of thrombolysis and anticoagulation treating lung embolism

Objective To evaluate long-term result of thromboysis and anticoagulation treating lung embolism. Methods 51 patients of acute lung embolism confirmed by pulmonary artery angiography or enhanced spiral CT were divided into two groups randomly. One was treated by anticoagulation. The other was treated by thromboysis within vein or catheter. After three years to observe blood gas analysis, and the pressure of right cardiac ventricle, right cardiac atrium, outflow tract of right cardiac ventricle, left cardiac ventricle, left cardiac atrium and pulmonary artery. Results The measurements of all of above indexes of two groups had no significant deviation. Conclusion The long-term result of thrombolysis and anticoagulation treating lung embolism are similar. Only anticoagulation of lung embolism without haemodynamics changes can obtain certain effect.