国产与进口玻璃酸钠关节内注射治疗膝关节骨关节炎的疗效分析

目的比较进口与国产玻璃酸钠治疗膝关节骨关节炎(OA)的疗效。方法纳入198例膝关节的患者,分为2组,A组采用进口玻璃酸钠,B组采用国产玻璃酸钠,膝关节腔内注射,1次·周-1,4次为1个疗程。结果对疼痛、炎症、关节活动等疗效观察指标进行评估,两组均能改善上述症状,而A组产品在疼痛与关节活动度改善疗效均优于B组,两组疗效间有显著性差异(P<0.05)。结论玻璃酸钠注射对膝骨关节炎的治疗确有疗效,进口玻璃酸钠在疗效上优于国产玻璃酸钠。

Outcome analysis on the therapeutic effect of imported and domestic sodium hyaluronate on knee osteoarthritis

OBJECTIVE To compare the curative effects on knee osteoarthritis(OA)between imported and domestic sodium by hyaluronate(SH).METHODS One hundred and ninety-eight patients with knee osteroarthritis were divided into 2 groups.Group A for imported one,and group B for domestic one.SH intra-capsular was injected once a week,and 4 weeks as a course.RESULTS According to the symptoms of pain,inflammation and impediment of daily activites,those symptoms improved in both groups,but group A gained better prospect,not only on the pain-curing but also the knee joint activity.CONCLUSIONS It seems that the intra-capsular injection of sodium hyaluronate using imported SH for OA has better outcome than the domestic one.