复方南星止痛膏联合玻璃酸钠治疗膝关节骨性关节炎25例

目的探讨复方南星止痛膏配合玻璃酸钠对膝关节骨性关节炎的疗效。方法将门诊骨关节炎患者75例（Ahlback1级）随机分成3组，每组25例。A组接受膝关节腔玻璃酸钠注射和复方南星止痛膏外敷，B组只接受膝关节腔玻璃酸钠注射，C组只接受复方南星止痛膏外敷。观察3组视觉模拟评分、西安大略和麦克马斯特大学骨关节炎调查量表（WOMAC）指数和中医证候，用以评价治疗效果。结果治疗后3组临床各项评分较治疗前均显著好转（P〈0．05），其中A组好转，较B组、C组具有显著性（P〈0．05），B组和C组之间无统计学差异（P〉0．05）。结论玻璃酸钠膝关节腔注射配合复方南星止痛膏外敷，较单用玻璃酸钠或复方南星止痛膏，对膝关节骨关节炎的治疗有更好的效果。

Clinical Study of Sodium Hyaluronate Coordinated by Compound Nanxing Analgesic Paster for Treating 25 Cases of Knee Osteoarthritis

Objective To explore the clinical efficacy of sodium hyaluronate coordinated by Compound Nanxing Analgesic Paster for treating knee osteoarthritis. Methods A total of 75 outpatients with osteoarthritis（Ahlback class 1） were collected and divided into three groups randomly,25 cases in each group. The group A received the knee cavity injection of sodium hyaluronate and external ap- plication of Compound Nanxing Analgesic Paster. The group B received only the knee cavity injection of sodium hyaluronate and the group C only received the external application of Compound Nanxing Analgesic Paster. The VAS score,C index （WOMA） and Chinese traditional medical symptom score were observed among 3 group for evaluating the curative effects. Results After treatment,the various scores in 3 groups were significantly improved than before treatment （P 〈 0. 05 ） , among them,the improvement in the group A was more significant than that in the group B and C,the difference had statistical significance （P 〈 0. 05）,but no statistical difference was found between the group B and C （P 〉 0. 05）. Conclusion Sodium hyaluronate coordinated by Compound Nanxing Analgesic Paster has better effect than sodium hyaluronate or Compound Nanxing Analgesic Paster alone for treating knee osteoarthritis.