住院患者鲍曼不动杆菌感染调查与防控措施

目的了解医院住院患者鲍曼不动杆菌感染的临床分布及耐药性变迁,为制定防控措施提供依据。方法通过实验室信息系统(LIS)和查看病人,每日监控住院患者鲍曼不动杆菌检出情况,并进行分析。结果从感染患者送检标本中共检出鲍曼不动杆菌431株,占病原菌检出总数的5.35%。感染患者主要分布于重症监护病房,构成比达72.85%;其次为呼吸科(10.67%)和神经内科(3.94%)。检出的鲍曼不动杆菌对12种临床常用抗菌药物的耐药率达到70%以上,2011年后检出的鲍曼不动杆菌对丁胺卡那等抗菌药物的耐药率呈明显下降趋势。在检出的431株鲍曼不动杆菌中,有290株为多重耐药菌株。结论医院住院患者感染鲍曼不动杆菌比例较高,该菌普遍耐药,且呈现多重耐药现象。

INVESTIGATION AND CONTROL MEASURES OF Acinetobacter baumannii INFECTION IN HOSPITALIZED PATIENTS

Objective To investigate the clinical distribution and antibiotic resistance change of Acinetobacter baumannii,in order to support formulation of guidelines for clinical management and infection prevention.Methods The staffs special in charge of infection monitored Acinetobacter baumannii detection everyday through Laboratory Information System(LIS),went to wards for investigation,and analyzed the clinical distribution and antibiotic resistance characteristics statistically.Results 431 strains of Acinetobacter baumannii were detected,accounting for 5.35% of total pathogens.The patients were mostly distributed in ICU(72.85%),secondly in respiratory department(10.67%) and neurology department(3.94%).The resistant rate to 12 kinds of routine antibiotics was above 70%,but with that to amikacin decreased obviously after 2011.290 strains were multiple drug resistant.Conclusions Acinetobacter baumannii is commonly detected in infected hospitalized patients,and shows general drug resistance and even multiple drug resistance.