噻托嗅铵治疗慢性阻塞性肺病的疗效观察

目的：评价吸入噻托嗅铵对慢性阻塞性肺病（COPD）的治疗作用。方法：将25例COPD患者分为2组，对照组给与常规综合治疗，治疗组给与噻托嗅铵千粉卉q吸入。结果：与治疗前相比，噻托溴铵组病人第1秒用力呼气容积（FEVI）和用力肺活量（FVC）均显著增加（P〈0．001）；治疗4周时。噻托溴铵组病人FEVI谷值明显上升（P〈0．01），常见药物不良反应为口干（1例。4％）。结论：噻托溴铵是治疗COPD病人有效和安全的支气管扩张药物，能明显改善患者的心累气紧症状。

The Curative Effect of Tiotropium Bromide in Treating Chronic Obstructive Pulmonary Disease

Objective: To evaluate the clinical effect of tiotropium bromide in treating COPD patient at stable stage.Methed: 25 patients with COPD were randomly divided into 2 groups,patients in experimental group were treated with tiotropium bromide and those in control group were treated with conventional therapy,The spiromerty was conducted at before treatment and 4 weeks after treatment.Result: Compared with the control group,Forced expiratory volum in second(FEV1),Forced vital capacity(FVC) were significantly increased after treatment in the tiotropium groups(p<0.01).The major adverse event in the tiotropium groups was dry mouth(4%).Conclusion: Tiotropium bromide can effectively improve lung function and clinical symptoms in COPD patient.