| TLC法快速鉴别保健品中非法添加的7种降糖类药物 |
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| 引用本文： | 汪泉,李翔,许威,肖华.TLC法快速鉴别保健品中非法添加的7种降糖类药物[J].安徽医药,2012,16(4):464-466. |
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| 作者姓名： | 汪泉 李翔 许威 肖华 |
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| 作者单位： | 广西中医学院药学院,广西,南宁,530001;安徽省食品药品检验所,安徽,合肥,230051 |
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| 摘 要： | 目的筛查保健品中非法添加的格列本脲和瑞格列奈等7种化学降糖药物。方法分别以环己烷-乙酸乙酯-甲醇-冰乙酸(14∶6∶1∶0.1)和环己烷∶乙酸乙酯∶冰乙酸(5∶5∶0.1)为展开剂进行筛查。结果 7种化学药物分离良好。结论该方法快速、简便,可用于保健品中非法添加降糖类药物的快速定性检查。
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| 关 键 词： | 保健品 降糖药物 薄层色谱法 |
Determination of seven antidiabetics illegally adulterated into health care products by TLC |
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| Institution: | WANG Quan,LI Xiang,XU Wei,et al(1.College of Pharmacy,Guangxi Traditional Chinese Medical University,Nanning 530001,China; 2.Anhui Provincial Institute for Food and Drug Control,Hefei 230051,China) |
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| Abstract: | Objective To screen 7 synthetic anti-diabetic drugs（Glibenclamide,Repaglinide,etc.） illegally added in health care products.Methods The cyclohexane-acetic ether-methanol-glacial acetic acid（14∶ 6∶ 1∶ 0.1）and cyclohexane-acetic ether-glacial acetic acid（5∶ 5∶ 0.1）were used as developers.Results Seven different antidiabetics were detected respectively by above two TLC system.Conclusion This method is reliable and suitable to determine antidiabetics adulterated into the health care products. |
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| Keywords: | health care products antidiabetics TLC |
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